巴西米纳斯吉拉斯州一家三级转诊医院治疗的患者中与肺结核和耐多药肺结核相关的因素。
Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil.
机构信息
. Hospital Júlia Kubitschek, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte (MG) Brasil.
. Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte (MG) Brasil.
出版信息
J Bras Pneumol. 2020 Mar 2;46(2):e20180386. doi: 10.36416/1806-3756/e20180386. eCollection 2020.
OBJECTIVE
To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital.
METHODS
This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospital, located in the city of Belo Horizonte, Brazil, between October of 2012 and October of 2014. We evaluated sociodemographic, behavioral, clinical, and radiological variables. The outcome considered to identify associations between tuberculosis and the explanatory variables was the treatment prescribed. To evaluate the associations between MDR-TB and the same explanatory variables, the change in MDR-TB treatment was considered.
RESULTS
The factors associated with tuberculosis were alcoholism, comorbidities, pulmonary cavitations, and a radiological pattern suggestive of tuberculosis. Cavitation and previous treatment for tuberculosis were associated with MDR-TB.
CONCLUSIONS
Despite the significant progress made in the fight against tuberculosis, there is a need for coordinated actions that include social protection measures and patient support.
目的
评估在一家三级转诊医院接受治疗的患者发生结核病和耐多药结核病（MDR-TB）的风险因素。
方法
这是一项基于 2012 年 10 月至 2014 年 10 月在巴西贝洛奥里藏特市的胡利娅·库比切克医院接受治疗的患者数据进行的横断面研究。我们评估了社会人口统计学、行为、临床和影像学变量。为了确定结核病与解释变量之间的关联，将规定的治疗方案视为结局。为了评估 MDR-TB 与相同解释变量之间的关联，将 MDR-TB 治疗的变化视为结局。
结果
与结核病相关的因素包括酗酒、合并症、肺空洞和提示结核病的影像学模式。空洞和既往结核病治疗与 MDR-TB 相关。
结论
尽管在结核病防治方面取得了重大进展，但仍需要采取协调行动，包括社会保护措施和患者支持。
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