Nikolenko J V, Kurshakova M M, Krasnov A N
Institute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia.
Dokl Biochem Biophys. 2019 Nov;489(1):407-410. doi: 10.1134/S1607672919060140. Epub 2020 Mar 4.
ENY2 protein of Drosophila melanogaster was previously discovered and characterized in our laboratory [1, 2]. It was found that ENY2 is a subunit of several multiprotein complexes and connects various stages of gene expression [3-5]. This work is devoted to studying the interaction of ENY2 with RNA helicase MLE. This interaction was confirmed by independent methods. Data indicating that this interaction is conserved in evolution and is important for the functioning of MLE in both sexes were obtained.
黑腹果蝇的ENY2蛋白先前已在我们实验室中被发现并进行了表征[1,2]。研究发现ENY2是几种多蛋白复合物的一个亚基,并连接基因表达的各个阶段[3-5]。这项工作致力于研究ENY2与RNA解旋酶MLE的相互作用。这种相互作用通过独立的方法得到了证实。获得的数据表明这种相互作用在进化过程中是保守的,并且对两性中MLE的功能都很重要。