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[中枢神经系统缺氧性损害新生儿的交感 - 肾上腺系统功能与酸碱平衡]

[Function of the sympathetico-adrenal system and the acid-base equilibrium in newborn infants with a hypoxic lesion of the central nervous system].

作者信息

Mialksoo M Ia, Tal'vik T A, Paiu A Iu, Kaasik A E, Sëzt A G

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(10):52-4.

PMID:3213331
Abstract

The function of the sympathetic-adrenal system was studied by measuring umbilical cord blood catecholamines in 31 full-term newborns with perinatal asphyxia and evidence of hypoxic-ischemic encephalopathy (HIE) and in 20 normal newborns. The results indicate that the full-term newborn responds to asphyxia with graded catecholamine release. The epinephrine concentration in newborns with moderate HIE is lower than in newborns with mild HIE, which may reflect decreased sympathetic-adrenal function due to prolonged asphyxia. Acid-base values in capillary blood and lumbar cerebrospinal fluid were determined in the babies with HIE, with the findings pointing to metabolic acidosis which was more expressed in cerebrospinal fluid.

摘要

通过测量31例足月围产期窒息且有缺氧缺血性脑病(HIE)证据的新生儿以及20例正常新生儿的脐带血儿茶酚胺,对交感 - 肾上腺系统的功能进行了研究。结果表明,足月新生儿对窒息的反应是儿茶酚胺分级释放。中度HIE新生儿的肾上腺素浓度低于轻度HIE新生儿,这可能反映了由于窒息时间延长导致交感 - 肾上腺功能下降。对患有HIE的婴儿测定了毛细血管血和腰椎脑脊液中的酸碱值,结果表明存在代谢性酸中毒,且在脑脊液中表现更为明显。

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Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(10):52-4.
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