The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, PA, USA.
Ophthalmic Consultants of Boston, Boston, MA, USA.
Surv Ophthalmol. 2020 Sep-Oct;65(5):589-591. doi: 10.1016/j.survophthal.2020.02.007. Epub 2020 Mar 3.
Vitreous floaters are common, related to age, myopia, genetic predisposition, and infiltration of the vitreous body. A subset of patients report symptoms impacting their quality of vision. Treatment with laser vitreolysis, the use of an Nd:YAG laser to vaporize the collagenous vitreous opacities appears to be used more frequently; however, data regarding long-term safety and effectiveness are lacking. We present currently available data regarding efficacy and safety, as well as additional considerations. Laser vitreolysis of symptomatic floaters should not be routinely performed without additional studies documenting its safety and long-term efficacy. Ideally, the procedure would be effective in most patients and be approved by the Food and Drug Administration based on the results of a Food and Drug Administration registration trial before widespread adoption.
玻璃体浮游物很常见，与年龄、近视、遗传易感性和玻璃体浸润有关。一部分患者报告说症状影响了他们的视力质量。采用激光玻璃体切除术治疗，即使用 Nd:YAG 激光蒸发胶原状玻璃体混浊，似乎更为常见；然而，关于长期安全性和有效性的数据却缺乏。我们目前提供有关疗效和安全性的资料，以及其他注意事项。在没有其他研究证明其安全性和长期疗效的情况下，不应常规对有症状的浮游物进行激光玻璃体切除术。理想情况下，该手术在大多数患者中都有效，并且在广泛应用之前，根据食品和药物管理局注册试验的结果，获得食品和药物管理局的批准。
