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Laser vitreolysis for symptomatic floaters is not yet ready for widespread adoption.激光玻璃体切除术治疗有症状的飞蚊症尚不成熟,尚未广泛采用。
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Efficacy and safety of early YAG laser vitreolysis for symptomatic vitreous floaters: the study protocol for a randomized clinical trial.早期 YAG 激光玻璃体切除术治疗症状性玻璃体浮游物的疗效和安全性:一项随机临床试验研究方案。
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Safety of YAG laser vitreolysis for intraocular tissues: analysis of postoperative complications.YAG 激光玻璃体切割术治疗眼内组织的安全性:术后并发症分析。
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本文引用的文献

1
Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy.钕钇铝石榴石激光玻璃体溶解术治疗有症状的玻璃体混浊:红外眼底摄影在评估治疗效果中的应用
J Ophthalmol. 2019 Jan 27;2019:8956952. doi: 10.1155/2019/8956952. eCollection 2019.
2
Iatrogenic Posterior Lens Capsule Rupture and Subsequent Complications due to Nd:YAG Laser Vitreolysis for Vitreous Floaters: A Case Report.因Nd:YAG激光玻璃体溶解术治疗玻璃体混浊导致医源性晶状体后囊破裂及后续并发症:一例报告
Ophthalmic Surg Lasers Imaging Retina. 2018 Nov 1;49(11):e214-e217. doi: 10.3928/23258160-20181101-21.
3
Novel OCT Application and Optimized YAG Laser Enable Visualization and Treatment of Mid- to Posterior Vitreous Floaters.新型光学相干断层扫描(OCT)应用与优化的钇铝石榴石(YAG)激光实现对中后段玻璃体混浊的可视化及治疗
Ophthalmic Surg Lasers Imaging Retina. 2018 Oct 1;49(10):806-811. doi: 10.3928/23258160-20181002-10.
4
Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin.使用奥克纤溶酶成功进行药物性玻璃体溶解术后出现的飞蚊症和对比敏感度降低
Am J Ophthalmol Case Rep. 2016 Aug 28;4:54-56. doi: 10.1016/j.ajoc.2016.08.005. eCollection 2016 Dec.
5
Psychological Distress in Patients with Symptomatic Vitreous Floaters.有症状玻璃体混浊患者的心理困扰
J Ophthalmol. 2017;2017:3191576. doi: 10.1155/2017/3191576. Epub 2017 Dec 10.
6
Reported Complications Following Laser Vitreolysis.激光玻璃体溶解术后报告的并发症。
JAMA Ophthalmol. 2017 Sep 1;135(9):973-976. doi: 10.1001/jamaophthalmol.2017.2477.
7
YAG Laser Vitreolysis vs Sham YAG Vitreolysis for Symptomatic Vitreous Floaters: A Randomized Clinical Trial.YAG激光玻璃体溶解术与假性YAG玻璃体溶解术治疗有症状玻璃体混浊的随机临床试验
JAMA Ophthalmol. 2017 Sep 1;135(9):918-923. doi: 10.1001/jamaophthalmol.2017.2388.
8
YAG Laser Vitreolysis-Is It as Clear as It Seems?YAG激光玻璃体溶解术——真有看上去那么简单吗?
JAMA Ophthalmol. 2017 Sep 1;135(9):924-925. doi: 10.1001/jamaophthalmol.2017.1683.
9
Rapid Cataract Progression after Nd:YAG Vitreolysis for Vitreous Floaters: A Case Report and Literature Review.钕:钇铝石榴石玻璃体溶解术治疗玻璃体混浊后白内障快速进展:病例报告及文献综述
Case Rep Ophthalmol. 2017 May 29;8(2):321-325. doi: 10.1159/000477159. eCollection 2017 May-Aug.
10
Nd:YAG laser vitreolysis versus pars plana vitrectomy for vitreous floaters.钕钇铝石榴石激光玻璃体溶解术与玻璃体切割术治疗玻璃体混浊的对比研究
Cochrane Database Syst Rev. 2017 Jun 1;6(6):CD011676. doi: 10.1002/14651858.CD011676.pub2.

YAG 激光玻璃体液化治疗飞蚊症的安全性和疗效:综述。

Safety and Efficacy of YAG Laser Vitreolysis for the Treatment of Vitreous Floaters: An Overview.

机构信息

Ophthalmology Department, University of Ioannina, Ioannina, Greece.

General Hospital "G. Genimatas- Ag. Dimitrios", Thessaloniki, Greece.

出版信息

Adv Ther. 2020 Apr;37(4):1319-1327. doi: 10.1007/s12325-020-01261-w. Epub 2020 Feb 21.

DOI:10.1007/s12325-020-01261-w
PMID:32086749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7140748/
Abstract

Emerging evidence has suggested that the entoptic phenomena associated with vitreous opacities (i.e. vitreous floaters) are more bothersome than previously believed. In addition, the prevalence of vitreous floaters is likely increasing due to the evolving global pandemic of myopia. The use of YAG laser vitreolysis for the treatment of annoying vitreous floaters has attracted significant attention in recent years as the technique offers a number of potential advantages. Unfortunately, the currently available evidence that is needed to guide clinical practice is both very limited and contradictory. As a consequence, the technique remains highly controversial. A review of the existing literature sheds light on patient- and treatment-related factors that may significantly affect both the effectiveness and the safety of the procedure. The current article discusses important aspects of key publications on the topic, offers suggestions for clinical practice, and highlights unmet needs that should be addressed by future research.

摘要

新出现的证据表明,与玻璃体混浊(即玻璃体浮游物)相关的内在视象现象比以前认为的更令人烦恼。此外,由于近视这一全球流行疾病的不断演变,玻璃体浮游物的患病率可能正在上升。近年来,YAG 激光玻璃体切除术治疗恼人的玻璃体浮游物引起了广泛关注,因为该技术具有许多潜在的优势。不幸的是,目前需要指导临床实践的证据非常有限且相互矛盾。因此,该技术仍然存在很大争议。对现有文献的回顾揭示了可能显著影响该手术的有效性和安全性的患者和治疗相关因素。本文讨论了关于该主题的重要文献的关键方面,为临床实践提供了建议,并强调了未来研究应解决的未满足需求。