National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan.
National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan..
Sci Total Environ. 2020 Jun 10;720:137549. doi: 10.1016/j.scitotenv.2020.137549. Epub 2020 Feb 25.
The occupational exposure of toxic metals is an important concern, because of its potential accumulation in living organisms, leading to long term toxic effects. The occupational and environmental contacts of toxic metals, cadmium (Cd) and lead (Pb) have been evaluated by determination of them in biological samples (blood and scalp hair) of adolescent and adults, workers of battery recycling and welding workshops. The age matched adolescent and adult residing in nonindustrial areas were also selected, termed as referent/control subjects. The blood and scalp hair samples of workers and controls were analyzed for Cd and Pb using graphite furnace atomic absorption spectrometry previously decomposed the matrices using acid mixture. The biochemical parameters of workers of both age groups were also evaluated. The average concentrations of Cd and Pb in blood and scalp hair samples of adolescent workers were three fold higher as compared with control subjects. The drinking water in containers of both workshops contained Pb and Cd in two to four and five to thirteen folds, respectively, higher than recommended permissible limits of WHO. The significant correlations between the blood lead levels and hemoglobin (%) in adolescent (r = -0.78). The positive correlation was observed among incidence of blood pressure with Pb and Cd concentrations in biological samples of workers (adults) (r = 0.65 to 0.83). These findings suggest that occupational exposure of toxic metals might be created adverse impacts on workers due to ill management of workshops.
有毒金属的职业暴露是一个值得关注的问题,因为其在生物体中的潜在积累可能导致长期的毒性影响。本研究通过测定电池回收和焊接车间工人及青少年和成年人的生物样本(血液和头发)中的镉(Cd)和铅(Pb)来评估有毒金属的职业和环境接触。还选择了居住在非工业区、年龄匹配的青少年和成年人作为参照/对照人群。使用石墨炉原子吸收光谱法分析工人和对照组的血液和头发样本中的 Cd 和 Pb,此前使用混合酸对基质进行了分解。还评估了两个年龄组工人的生化参数。与对照组相比,青少年工人血液和头发样本中的 Cd 和 Pb 平均浓度高 3 倍。两个车间的饮用水容器中的 Pb 和 Cd 含量分别比世界卫生组织推荐的可接受限量高 2 到 4 倍和 5 到 13 倍。青少年(r = -0.78)血液铅水平与血红蛋白(%)之间存在显著相关性。在工人(成年人)的生物样本中,血压与 Pb 和 Cd 浓度之间存在正相关(r = 0.65 至 0.83)。这些发现表明,由于车间管理不善,有毒金属的职业暴露可能对工人造成不良影响。