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[2013年至2017年河南省城市地区低剂量计算机断层扫描肺癌筛查效果分析]

[Analysis of the efficacy of lung cancer screening in urban areas of Henan Province by low-dose computed tomography from 2013 to 2017].

作者信息

Guo L W, Liu S Z, Zhang S K, Yang F N, Wu Y, Zheng L Y, Chen Q, Cao X Q, Sun X B

机构信息

Henan Office for Cancer Control and Research, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China.

Department of Thoracic Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2020 Feb 23;42(2):155-159. doi: 10.3760/cma.j.issn.0253-3766.2020.02.013.

Abstract

To evaluate the efficacy of lung cancer screening in urban areas of Henan province by low-dose computed tomography (LDCT) from 2013 to 2017. A cluster sampling method was used to select the residents of 40-74 years old in Henan province to investigate the risk factors and conduct lung cancer risk assessment. Subjects with high risk of lung cancer received LDCT for screening. A total of 179 002 residents completed the lung cancer risk assessment, and 35 672 subjects were identified as high risk of lung cancer, with a high risk rate of 19.93%. A total of 13 383 subjects with high risk received LDCT, and the screening rate was 37.52%. There were 786 cases diagnosed as positive nodules, and the detection rate was 5.87%. Among them, 755 cases of solid/partial solid nodule were ≥5 mm, 23 cases of non-solid nodules were ≥8 mm, 8 cases were intratracheal nodules, and 115 cases were diagnosed as suspicious lung cancer. The detection rate in males was 6.74%, which was higher than 5.02% in females. The detection rate was positively related with age (<0.05). The application of LDCT is a useful screening method which can elevate the early detection rate of positive nodules and other related diseases in lungs. In the future, males and older populations should be paid more attention to improve screening efficacy.

摘要

评估2013年至2017年河南省城市地区采用低剂量计算机断层扫描(LDCT)进行肺癌筛查的效果。采用整群抽样方法选取河南省40 - 74岁居民,调查危险因素并进行肺癌风险评估。肺癌高危人群接受LDCT筛查。共有179002名居民完成肺癌风险评估,35672名受试者被确定为肺癌高危人群,高危率为19.93%。共有13383名高危受试者接受了LDCT检查,筛查率为37.52%。诊断为阳性结节的有786例,检出率为5.87%。其中,755例实性/部分实性结节≥5mm,23例非实性结节≥8mm,8例气管内结节,115例被诊断为疑似肺癌。男性检出率为6.74%,高于女性的5.02%。检出率与年龄呈正相关(<0.05)。LDCT的应用是一种有效的筛查方法,可提高肺部阳性结节及其他相关疾病的早期检出率。未来,应更加关注男性和老年人群以提高筛查效果。

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