Lin Yanping, Ma Jie, Feng Jun, Zhang Qiang, Huang Yunchao
Yunnan Cancer Hospital/The Third Affiliated Hospital of Kunming Medical University/Yunnan Cancer Center, Kunming 650118, China.
Zhongguo Fei Ai Za Zhi. 2019 Jul 20;22(7):413-418. doi: 10.3779/j.issn.1009-3419.2019.07.02.
Lung cancer screening is an effective measure to reduce lung cancer mortality. Currently, lung cancer screening is recommended internationally and nationally. China had launched a large-scale early diagnosis and early treatment of rural and urban lung cancer in 2009 and 2012. Yunnan Province participated in related projects in 2009 and 2014, but the results of large-scale lung cancer screening have not been reported in Yunnan Province. In this study, we participated in the National Key Public Health Program, Cancer Screening Program in Urban China and analyzed the results of lung cancer screening in 10,154 urban residents in Kunming, Yunnan Province from 2014 to 2018, and evaluated the screening effect of early diagnosis and treatment of lung cancer in urban.
A total of 31,824 people with high risk of lung cancer were evaluated with 40-74 year-old population in Kunming. A high-risk group underwent low-dose spiral computed tomography (CT) scan of the chest, and analyze the high risk rate and detection rate. A total of 150,535 questionnaires were completed in 5 years, and 31,824 people with high risk of lung cancer were evaluated.
The high-risk rate was 21.14%. A total of 10,154 low-dose spiral CT screenings were performed, with a participation rate of 31.91%. The detection rate of intrapulmonary nodules was 22.28% (2,262/10,154), of which the detection rate of <5 mm solid/partial solid nodules was 11.30% (1,332/10,154) and the detection rate of <8 mm non-solid nodules was 2.20% (219/10,154). The positive nodule detection rate was 7.00% (711/10,154), the suspected lung cancer detection rate was 0.60% (59/10,154), and the lung cancer detection rate was 0.27% (27/10,154). The detection rate of the positive nodules, <8 mm non-solid nodules and suspected lung cancer in male were significantly higher than that in female, and the positive nodules, <5 mm solid nodules, suspected lung cancer and confirmed lung cancer detection rate increased with age.
Low-dose spiral CT is suitable for screening of high-risk populations of lung cancer, which is helpful for early detection of positive nodules and related diseases in the lungs. It is necessary to pay attention to the screening of lung cancer in people over 60 years old. Understand the lung health status of residents in Kunming. Raise awareness of lung cancer prevention and treatment among residents, and improve the rate of early diagnosis and treatment of lung cancer.
肺癌筛查是降低肺癌死亡率的有效措施。目前，肺癌筛查在国际和国内均被推荐。中国于2009年和2012年分别启动了城乡肺癌大规模早期诊断和早期治疗项目。云南省于2009年和2014年参与了相关项目，但云南省大规模肺癌筛查的结果尚未见报道。在本研究中，我们参与了国家重点公共卫生项目——中国城市癌症筛查项目，并分析了2014年至2018年云南省昆明市10154名城市居民的肺癌筛查结果，评估了城市肺癌早期诊断和治疗的筛查效果。
对昆明市40 - 74岁有肺癌高危风险的31824人进行评估。高危人群接受胸部低剂量螺旋计算机断层扫描（CT），并分析高危率和检出率。5年共完成150535份问卷，评估31824名有肺癌高危风险的人。
高危率为21.14%。共进行了10154次低剂量螺旋CT筛查，参与率为31.91%。肺内结节检出率为22.28%（2262/10154），其中<5mm实性/部分实性结节检出率为11.30%（1332/10154），<8mm非实性结节检出率为2.20%（219/10154）。阳性结节检出率为7.00%（711/10154），疑似肺癌检出率为0.60%（59/10154），肺癌检出率为0.27%（27/10154）。男性阳性结节、<8mm非实性结节及疑似肺癌的检出率显著高于女性，阳性结节、<5mm实性结节、疑似肺癌及确诊肺癌的检出率随年龄增加而升高。
低剂量螺旋CT适用于肺癌高危人群的筛查，有助于早期发现肺部阳性结节及相关疾病。有必要关注60岁以上人群的肺癌筛查。了解昆明市居民的肺部健康状况。提高居民肺癌防治意识，提高肺癌早期诊断和治疗率。
