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使用氯己定或紫外线C辐射清洁愈合基台对种植体周围黏膜炎症的控制。双盲随机临床试验。

Control of Peri-Implant Mucous Inflammation by Using Chlorhexidine or Ultraviolet C Radiation for Cleaning Healing Abutments. Double-Blind Randomized Clinical Trial.

作者信息

Sanchez-Perez Arturo, Nicolas-Silvente Ana I, Sanchez-Matas Carmen, Cascales-Pina Elena, Macia-Manresa Vanesa, Romanos Georgios E

机构信息

D.D.S., Department of Periodontology, Medicine and Dentistry Faculty, Murcia University, 30008 Murcia, Spain.

D.D.S., Department of Restorative Dentistry, Medicine and Dentistry Faculty, Murcia University, 30008 Murcia, Spain.

出版信息

Materials (Basel). 2020 Mar 3;13(5):1124. doi: 10.3390/ma13051124.

DOI:10.3390/ma13051124
PMID:32138236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7084961/
Abstract

Two-phase implants must be exposed to the external environment after the period of osteointegration has elapsed. For this purpose, a healing abutment is placed passing through the mucosa while forming the emergence profile. The continuous connection and disconnection can lead to an alteration in the tissue maturation, both because of the contact of bacterial plaque and because of the mechanical trauma that involves its manipulation, manifesting with different degrees of erythema or bleeding. To assess whether this epithelium disruption can be counteracted, a blinded study design was developed on 150 unitary implant patients divided into three groups (n = 50), applying chlorhexidine (group 1), ultraviolet C (UV-C) at a wavelength of 254 nm (group 2)and no treatment as a control group (group 3), during each of the disconnections and connections during the prosthodontic treatment (1 time per week for four weeks). All groups showed a better epithelium aspect at the end of the evaluation. Although there were no statistically significant differences in the degree of inflammation, the UV-C treated group had the lowest plaque accumulation, and the highest was for the chlorhexidine-treated group.

摘要

两阶段种植体在骨整合期结束后必须暴露于外部环境。为此,在形成龈缘外形时,将愈合基台穿过黏膜放置。连续连接和断开连接会导致组织成熟度改变,这既是由于细菌菌斑的接触,也是由于涉及操作的机械创伤,表现为不同程度的红斑或出血。为了评估这种上皮破坏是否可以抵消,对150名单颗种植体患者进行了一项盲法研究设计,将其分为三组(n = 50),在修复治疗期间每次连接和断开连接时(四周内每周一次),分别应用氯己定(第1组)、波长为254 nm的紫外线C(UV-C,第2组),第3组不进行治疗作为对照组。在评估结束时,所有组的上皮状况均有所改善。尽管炎症程度没有统计学上的显著差异,但紫外线C治疗组的菌斑堆积最少,氯己定治疗组的菌斑堆积最多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/e3b2d1609e04/materials-13-01124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/455d27a7606c/materials-13-01124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/1f8b1c28408d/materials-13-01124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/e3b2d1609e04/materials-13-01124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/455d27a7606c/materials-13-01124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/1f8b1c28408d/materials-13-01124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11a1/7084961/e3b2d1609e04/materials-13-01124-g003.jpg

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本文引用的文献

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Implant-abutment connection as contributing factor to peri-implant diseases.种植体-基台连接是导致种植体周围疾病的因素之一。
Periodontol 2000. 2019 Oct;81(1):152-166. doi: 10.1111/prd.12289.
2
Peri-Implant Bone Resorption during Healing Abutment Placement: The Effect of a 0.20% Chlorhexidine Gel vs. Placebo-A Randomized Double Blind Controlled Human Study.种植体周围骨吸收的愈合期:0.20%洗必泰凝胶与安慰剂的对比——一项随机双盲对照的人体研究。
Biomed Res Int. 2018 Oct 16;2018:5326340. doi: 10.1155/2018/5326340. eCollection 2018.
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The micromechanical behavior of implant-abutment connections under a dynamic load protocol.
种植体-基台连接在动态负载方案下的微观力学行为。
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The influence of repeated abutment changes on peri-implant tissue stability: 3-year post-loading results from a multicentre randomised controlled trial.种植体基台反复更换对种植体周围组织稳定性的影响:一项多中心随机对照试验的3年加载后结果
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Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.洗必泰漱口水作为牙龈健康的辅助治疗方法。
Cochrane Database Syst Rev. 2017 Mar 31;3(3):CD008676. doi: 10.1002/14651858.CD008676.pub2.
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Antimicrobial Agents Used in the Treatment of Peri-Implantitis Alter the Physicochemistry and Cytocompatibility of Titanium Surfaces.用于治疗种植体周围炎的抗菌剂会改变钛表面的物理化学性质和细胞相容性。
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