Valsan Swetha, Biniraj K R, Emmatty Rishi, Paul Tony P, Jose Priya, Divyasree K A
Department of Clinical Periodontology and Oral Implantology, Royal Dental College, Palakkad, Kerala, India.
J Indian Soc Periodontol. 2022 Nov-Dec;26(6):585-590. doi: 10.4103/jisp.jisp_382_21. Epub 2022 Nov 14.
An experimental study was designed to evaluate the effect of chlorhexidine gluconate chips on clinical status of peri-implant mucosa and plaque formation on healing abutments following single-stage implant surgeries.
Twenty-eight single-stage implant sites were grouped into 14 test and control sites. The study commences from the time of suture removal following surgery, designated as day 0. Chlorhexidine chip insertion into peri-implant sulcus in test sites was done on day 0, 10, and 20. Peri-implant crevicular fluid was collected on day 0, 10, 20, and 30 for biochemical estimation of aspartate aminotransferase (AST). The modified sulcus bleeding index (mBI) score was obtained in both test and control sites on day 10, 20, and 30. On day 30, all the healing abutments were unscrewed and sent for stereomicroscopic analysis to assess the plaque formation on its surface.
Statistically significant difference was not observed in AST levels and mBI in both test and control groups in various time intervals. In the stereomicroscopic assessment of healing abutment, mild grade of plaque accumulation was seen in three samples in test group, one sample in control group, and severe grade was seen in six samples in test group and nine samples in the control group.
Inflammatory condition of peri-implant mucosa and plaque retentive properties on healing abutment surface were found to have reduced with the usage of chlorhexidine gluconate chips. However, the study failed to establish a statistically significant correlation of these observations.
设计一项实验研究以评估葡萄糖酸氯己定芯片对单阶段种植手术后种植体周围黏膜临床状况及愈合基台上菌斑形成的影响。
28个单阶段种植部位被分为14个试验组和14个对照组。研究从手术后拆线时间开始,定为第0天。试验组在第0天、第10天和第20天在种植体周围龈沟插入氯己定芯片。在第0天、第10天、第20天和第30天收集种植体周围龈沟液,用于天冬氨酸转氨酶(AST)的生化测定。在第10天、第20天和第30天在试验组和对照组获得改良龈沟出血指数(mBI)评分。在第30天,拧下所有愈合基台并送去进行体视显微镜分析,以评估其表面的菌斑形成情况。
在不同时间间隔,试验组和对照组的AST水平和mBI均未观察到统计学上的显著差异。在愈合基台的体视显微镜评估中,试验组有3个样本、对照组有1个样本可见轻度菌斑积聚,试验组有6个样本、对照组有9个样本可见重度菌斑积聚。
发现使用葡萄糖酸氯己定芯片可降低种植体周围黏膜的炎症状况以及愈合基台表面的菌斑滞留特性。然而,该研究未能证实这些观察结果具有统计学上的显著相关性。