Morizumi Hiroshi, Sano Toshiaki, Tsuyuguchi Masaru, Yoshinarl Toshiko, Morimoto Shigetoshi
Department of Pathology, Tokushima Municipal Hospital, Tokushima, Japan.
Department of Pathology, University of Tokushima, School of Medicine, Tokushima, Japan.
Endocr Pathol. 1991 Dec;2(4):226-229. doi: 10.1007/BF02915212.
A case of localized adiposity of the thyroid in a 35-year-old woman with a long history of steroid therapy for nephrotic syndrome is reported. A well-demarcated yellowish mass measuring 2 cm in diameter was found in the upper portion of the right lobe of the thyroid. Microscopically, this lesion was composed of mature adipose tissue partially mixed with thyroid tissue and had no distinct capsule. The nontumorous thyroid tissue showed features of Hashimoto's thyroiditis. At least two factors-hamartomatous malformation and metabolic disturbance-may be involved in the histogenesis of this localized adiposity.
报告了一例35岁女性甲状腺局部脂肪沉积病例，该患者有长期使用类固醇治疗肾病综合征的病史。在甲状腺右叶上部发现一个边界清晰的淡黄色肿块，直径2厘米。显微镜下，该病变由成熟脂肪组织与甲状腺组织部分混合组成，无明显包膜。非肿瘤性甲状腺组织表现为桥本甲状腺炎的特征。这种局部脂肪沉积的组织发生可能涉及至少两个因素——错构瘤畸形和代谢紊乱。
