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超越抑郁:行为激活对抑郁、焦虑和激活影响的元分析

Looking beyond depression: a meta-analysis of the effect of behavioral activation on depression, anxiety, and activation.

机构信息

University of Texas at Austin, Austin, TX, USA.

Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

出版信息

Psychol Med. 2021 Jul;51(9):1491-1504. doi: 10.1017/S0033291720000239. Epub 2020 Mar 6.

Abstract

BACKGROUND

Depression is a prevalent and impairing condition. Behavioral activation (BA) is a parsimonious, cost-effective, and easily disseminated psychological intervention for depression. The current meta-analysis expands on the existing literature supporting the efficacy of BA for depression by examining the effects of BA on additional relevant outcomes for patients with depression, namely the reduction in anxiety symptoms and increase in activation.

METHODS

Randomized controlled trials of BA for depression compared to active and inactive control were identified via a systematic review. Effect sizes using Hedges's g were calculated for each outcome compared to both active and inactive control using random effects models. Subgroup analyses were used to examine the inclusion of a discussion of values as a moderator of depression symptom outcome in BA.

RESULTS

Twenty-eight studies were included. Meta-analyses of symptom change between groups from baseline-to-post intervention indicated that BA outperformed inactive control conditions for improvements in depression (g = 0.83), anxiety (g = 0.37), and activation (g = 0.64). The difference between BA and active control conditions was not significant for improvements in depression (g = 0.15), anxiety (g = 0.03), and activation (g = 0.04). There was no evidence for a discussion of values augmenting BA efficacy. Study quality was generally low, and there was evidence of publication bias.

CONCLUSIONS

In addition to improving depression, BA shows efficacy for reducing symptoms of anxiety and increasing activation. BA may not offer better outcomes relative to other active interventions. There is room for improvement in the quality of research in this area.

摘要

背景

抑郁症是一种普遍且会造成损害的疾病。行为激活(BA)是一种简洁、经济有效的心理干预方法,可广泛应用于抑郁症的治疗。本项荟萃分析通过考察行为激活对抑郁症患者其他相关结局的影响,进一步证实了其治疗抑郁症的有效性,这些结局包括焦虑症状的减轻和活动度的增加。

方法

通过系统综述,确定了与积极对照和消极对照相比,针对抑郁症的行为激活的随机对照试验。使用随机效应模型,针对每种结局,与积极对照和消极对照相比,计算效应量 Hedges'g。采用亚组分析,考察将价值讨论纳入行为激活治疗抑郁症结局的调节因素。

结果

共纳入 28 项研究。组间从基线到干预后的症状变化的荟萃分析表明,与消极对照相比,行为激活在改善抑郁症状(g=0.83)、焦虑症状(g=0.37)和活动度(g=0.64)方面表现出更好的疗效。与积极对照相比,行为激活在改善抑郁症状(g=0.15)、焦虑症状(g=0.03)和活动度(g=0.04)方面的差异不显著。没有证据表明价值讨论可以增强行为激活的疗效。研究质量普遍较低,存在发表偏倚的证据。

结论

除了改善抑郁症状外,行为激活对减轻焦虑症状和增加活动度也具有疗效。与其他积极干预相比,行为激活可能不会提供更好的结果。在这一领域的研究质量还有改进的空间。

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