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急性静脉曲张出血时紧急经颈静脉肝内门体分流术的建立

Emergent Transjugular Intrahepatic Portosystemic Shunt Creation in Acute Variceal Bleeding.

作者信息

Pandhi Mithil B, Kuei Andrew J, Lipnik Andrew J, Gaba Ron C

机构信息

Department of Radiology, University of Illinois at Chicago, Chicago, Illinois.

Division of Interventional Radiology, University of Illinois at Chicago, Chicago, Illinois.

出版信息

Semin Intervent Radiol. 2020 Mar;37(1):3-13. doi: 10.1055/s-0039-3402015. Epub 2020 Mar 4.

DOI:10.1055/s-0039-3402015
PMID:32139965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7056345/
Abstract

Emergent transjugular intrahepatic portosystemic shunt (TIPS) creation is most commonly employed in the setting of acute variceal hemorrhage. Given a propensity for decompensation, these patients often require a multidisciplinary, multimodal approach involving prompt diagnosis, pharmacologic therapy, and endoscopic intervention. While successful in the majority of cases, failure to medically control initial bleeding can prompt interventional radiology consultation for emergent portal decompression via TIPS creation. This article discusses TIPS creation in emergent, acute variceal hemorrhage, reviewing the natural history of gastroesophageal varices, presentation and diagnosis of acute variceal hemorrhage, pharmacologic therapy, endoscopic approaches, patient selection and risk stratification for TIPS, technical considerations for TIPS creation, adjunctive embolotherapy, and the role of salvage TIPS versus early TIPS in acute variceal hemorrhage.

摘要

急诊经颈静脉肝内门体分流术(TIPS)最常用于急性静脉曲张出血的情况。鉴于这些患者有失代偿的倾向,通常需要多学科、多模式的方法,包括及时诊断、药物治疗和内镜干预。虽然大多数情况下是成功的,但如果药物治疗未能控制初始出血,可能会促使介入放射科会诊,通过创建TIPS进行急诊门静脉减压。本文讨论了急诊急性静脉曲张出血时TIPS的创建,回顾了食管胃静脉曲张的自然病史、急性静脉曲张出血的表现和诊断、药物治疗、内镜方法、TIPS的患者选择和风险分层、TIPS创建的技术考虑、辅助栓塞治疗以及挽救性TIPS与早期TIPS在急性静脉曲张出血中的作用。

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本文引用的文献

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Long-term follow-up of transjugular intrahepatic portosystemic shunt (TIPS) with stent-graft.经覆膜支架的经颈静脉肝内门体分流术(TIPS)的长期随访。
Diagn Interv Radiol. 2019 Sep;25(5):346-352. doi: 10.5152/dir.2019.18416.
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Management of acute variceal hemorrhage.急性静脉曲张出血的管理
F1000Res. 2019 Jun 25;8. doi: 10.12688/f1000research.18807.1. eCollection 2019.
3
Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial.早期 TIPS(经颈静脉肝内门体分流术)联合覆膜支架与标准治疗对肝硬化急性静脉曲张出血患者的随机对照试验。
Lancet Gastroenterol Hepatol. 2019 Aug;4(8):587-598. doi: 10.1016/S2468-1253(19)30090-1. Epub 2019 May 29.
4
Evaluation of model performance to predict survival after transjugular intrahepatic portosystemic shunt placement.评估模型在预测经颈静脉肝内门体分流术放置后生存情况的表现。
PLoS One. 2019 May 23;14(5):e0217442. doi: 10.1371/journal.pone.0217442. eCollection 2019.
5
Emergency Transjugular Intrahepatic Portosystemic Shunt: an Effective and Safe Treatment for Uncontrolled Variceal Bleeding.急诊经颈静脉肝内门体分流术:治疗未控制的静脉曲张出血的有效且安全的方法。
J Gastrointest Surg. 2019 Nov;23(11):2193-2200. doi: 10.1007/s11605-019-04146-8. Epub 2019 Feb 21.
6
Adjuvant Transjugular Variceal Occlusion at Creation of a Transjugular Intrahepatic Portosystemic Shunt (TIPS): Efficacy and Risks of Bucrylate Embolization.经颈静脉肝内门体分流术(TIPS)建立时辅助经颈静脉曲张静脉闭塞术:丁基丙烯酸酯栓塞的疗效和风险
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