Adjepong Dennis, Malik Bilal Haider
Neurological Surgery, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Cureus. 2020 Jan 28;12(1):e6795. doi: 10.7759/cureus.6795.
Chronic traumatic encephalopathy (CTE) results from brain injuries and traumas due to accelerated impacts on the head. In severe cases, the diseases cause brain damage, given the head trauma. On the other hand, vasculitis occurs through antibodies that mistake protein vessels as foreign, hence fighting them and resulting in their damage. Examination is usually conducted through blood tests, with antibodies being identified in the antineutrophil cytoplasm. It is unfortunate that its devastating effects also affect the brain of a human, hence leading to dis-functioning. When vasculitis is left untreated, it results in multiple adverse effects on the human body and health both in the short term and in the long term. This study aims to bring to the awareness of neurosurgeons the associations between CTE and vasculitis. This study has proved that there is a close correlation between the progression of CTE and vasculitis. The inflammatory of the blood vessels, as witnessed in vasculitis, increases the risk factors for CTE. The scaling of the vessels and manifestation of different vasculitis conditions in active central nervous system cells results in the worsening of neurodegeneration of the CTE disease.
慢性创伤性脑病（CTE）是由头部加速撞击导致的脑损伤和创伤引起的。在严重情况下，鉴于头部创伤，这些疾病会导致脑损伤。另一方面，血管炎是通过抗体将蛋白质血管误认为外来物而发生的，因此会攻击它们并导致其损伤。通常通过血液检测进行检查，在抗中性粒细胞胞浆中可识别出抗体。不幸的是，其破坏性影响也会影响人类大脑，从而导致功能失调。当血管炎得不到治疗时，无论在短期还是长期都会对人体和健康产生多种不良影响。本研究旨在让神经外科医生了解CTE与血管炎之间的关联。这项研究已证明CTE的进展与血管炎之间存在密切相关性。如在血管炎中所见，血管的炎症增加了CTE的风险因素。血管的扩张以及活跃的中枢神经系统细胞中不同血管炎状况的表现会导致CTE疾病神经退行性变的恶化。
