McKee Ann C, Alosco Michael L, Huber Bertrand R
Department of Pathology and Laboratory Medicine, VA Boston Healthcare System, 150 South Huntington Avenue, Boston, MA 02130, USA; Department of Neurology, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA; CTE Program, Alzheimer's Disease Center, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA; Department of Pathology, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA.
Department of Neurology, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA; CTE Program, Alzheimer's Disease Center, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA.
Neurosurg Clin N Am. 2016 Oct;27(4):529-35. doi: 10.1016/j.nec.2016.05.009.
Chronic traumatic encephalopathy (CTE) is a distinctive neurodegenerative disease that occurs as a result of repetitive head impacts. CTE can only be diagnosed by postmortem neuropathologic examination of brain tissue. CTE is a unique disorder with a pathognomonic lesion that can be reliably distinguished from other neurodegenerative diseases. CTE is associated with violent behaviors, explosivity, loss of control, depression, suicide, memory loss and cognitive changes. There is increasing evidence that CTE affects amateur athletes as well as professional athletes and military veterans. CTE has become a major public health concern.
慢性创伤性脑病（CTE）是一种独特的神经退行性疾病，由重复性头部撞击所致。CTE只能通过对脑组织进行死后神经病理学检查来诊断。CTE是一种具有特征性病变的独特病症，可与其他神经退行性疾病可靠区分。CTE与暴力行为、易激惹、失控、抑郁、自杀、记忆力减退和认知改变有关。越来越多的证据表明，CTE会影响业余运动员、职业运动员和退伍军人。CTE已成为一个重大的公共卫生问题。
