Yee Maria Ruiza, Espiridion Eduardo D, Gurski John
Psychiatry, Reading Hospital Tower Health, West Reading, USA.
Cureus. 2020 Jan 28;12(1):e6801. doi: 10.7759/cureus.6801.
Tardive dyskinesia (TD) is a serious and often irreversible involuntary muscle movement that involves the face, lips, tongue, trunk, and extremities. TD is a risk in the use of antipsychotic medications, whether it is typical or first generation or atypical or second-generation antipsychotic. The risk is highest in patients receiving long-term antipsychotic treatment. Before the availability of valbenazine, clozapine was used to reverse or at least ameliorate TD. We report a case of a patient on long-term antipsychotic treatment whose TD was initially reversed by clozapine but was completely reversed by valbenazine.
迟发性运动障碍（TD）是一种严重且通常不可逆的不自主肌肉运动，累及面部、嘴唇、舌头、躯干和四肢。使用抗精神病药物会有TD的风险，无论是典型（第一代）还是非典型（第二代）抗精神病药物。接受长期抗精神病治疗的患者风险最高。在缬苯那嗪问世之前，氯氮平被用于逆转或至少改善TD。我们报告一例长期接受抗精神病治疗的患者，其TD最初通过氯氮平得到逆转，但最终通过缬苯那嗪完全逆转。
