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Drug-Induced Liver Injury by Selective Androgenic Receptor Modulators.
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Selective Androgen Receptor Modulators: An Emerging Liver Toxin.
J Clin Transl Hepatol. 2023 Feb 28;11(1):188-196. doi: 10.14218/JCTH.2022.00207. Epub 2022 Nov 4.
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Comparative safety evaluation of selective androgen receptor modulators and anabolic androgenic steroids.
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Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications.
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Selective Androgen Receptor Modulator-Induced Liver Injury in Active Duty Male.
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Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator.
ACG Case Rep J. 2021 Jan 7;8(1):e00518. doi: 10.14309/crj.0000000000000518. eCollection 2021 Jan.
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Pharmacodynamics of selective androgen receptor modulators.
J Pharmacol Exp Ther. 2003 Mar;304(3):1334-40. doi: 10.1124/jpet.102.040840.
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Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis.
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Selective androgen receptor modulators: the future of androgen therapy?
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2
Silent Threats to the Liver: Acute Hepatotoxicity Attributed to Selective Androgen Receptor Modulators (SARMs).
Cureus. 2025 Jun 7;17(6):e85500. doi: 10.7759/cureus.85500. eCollection 2025 Jun.
3
Ligandrol lowers endurance and negatively affects lipid and hormonal profile of male rats.
Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar 15. doi: 10.1007/s00210-025-04028-8.
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Ostarine blunts the effect of endurance training on submaximal endurance in rats.
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Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases.
Eur J Clin Pharmacol. 2024 Feb;80(2):185-202. doi: 10.1007/s00228-023-03592-3. Epub 2023 Dec 7.

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2
Causality assessment for suspected DILI during clinical phases of drug development.
Drug Saf. 2014 Nov;37 Suppl 1(Suppl 1):S47-56. doi: 10.1007/s40264-014-0185-4.
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ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury.
Am J Gastroenterol. 2014 Jul;109(7):950-66; quiz 967. doi: 10.1038/ajg.2014.131. Epub 2014 Jun 17.
5
The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men.
J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):87-95. doi: 10.1093/gerona/gls078. Epub 2012 Mar 28.

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