Centre for Agricultural Research, Institute for Veterinary Medical Research, Hungarian Academy of Sciences, P.O. Box 18, Budapest, 1581, Hungary.
Instituto de Patobiología, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay.
Arch Virol. 2020 May;165(5):1215-1218. doi: 10.1007/s00705-020-04570-1. Epub 2020 Mar 5.
A novel lymphocystivirus causing typical signs of lymphocystis virus disease in whitemouth croaker (Micropogonias furnieri) on the coast of Uruguay was detected and described recently. Based on genetic analysis of some partially sequenced core genes, the virus seemed to differ from previously described members of the genus Lymphocystivirus. In this study, using next-generation sequencing, the whole genome of this virus was sequenced and analysed. The complete genome was found to be 211,086 bp in size, containing 148 predicted protein-coding regions, including the 26 core genes that seem to have a homologue in every iridovirus genome sequenced to date. Considering the current species demarcation criteria for the family Iridoviridae (genome organization, G+C content, amino acid sequence similarity, and phylogenetic relatedness of the core genes), the establishment of a novel species ("Lymphocystis disease virus 4") in the genus Lymphocystivirus is suggested.
最近在乌拉圭沿海的白口黑鲈（Micropogonias furnieri）中发现并描述了一种引起典型淋巴囊肿病毒病的新型淋巴囊肿病毒。基于部分测序核心基因的遗传分析，该病毒似乎与先前描述的淋巴囊肿病毒属成员不同。在这项研究中，使用下一代测序技术对该病毒的全基因组进行了测序和分析。发现完整基因组大小为 211,086 bp，包含 148 个预测的蛋白编码区，包括 26 个核心基因，这些基因似乎在迄今为止测序的每种虹彩病毒基因组中都有同源物。考虑到虹彩病毒科的现行种分类标准（基因组组织、G+C 含量、氨基酸序列相似性和核心基因的系统发育关系），建议在淋巴囊肿病毒属中建立一个新种（“淋巴囊肿病毒 4”）。
