压力重重的开端，影响深远。
Stressful Beginnings with Long-Term Consequences.
作者信息
Consiglio Camila Rosat, Brodin Petter
机构信息
Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17121, Sweden.
Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17121, Sweden; Unit of Pediatric Rheumatology, Karolinska University Hospital, Solna SE-17176, Sweden.
出版信息
Cell. 2020 Mar 5;180(5):820-821. doi: 10.1016/j.cell.2020.02.021.
Early-life stress can have long-term health consequences, but the mechanisms of this are unknown. In this issue of Cell, Hong et al. demonstrate one such mechanism linking perinatal corticosteroid exposure to reduced CD8 T cell function later in life and impaired anti-cancer and anti-bacterial immune responses.
早年生活压力可能会产生长期的健康后果，但其机制尚不清楚。在本期《细胞》杂志中，洪等人展示了一种这样的机制，即将围产期接触皮质类固醇与生命后期CD8 T细胞功能降低以及抗癌和抗菌免疫反应受损联系起来。
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