Department of Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium.
Department of Public Health and Primary Care, Laboratory of Gerontology and Geriatrics, KU Leuven, Leuven, Belgium.
BMC Gastroenterol. 2020 Mar 6;20(1):63. doi: 10.1186/s12876-020-01198-y.
Pseudoachalasia is a rare disorder which has clinical, radiographic, and manometric findings that are often indistinguishable from primary achalasia. It is usually associated with malignancy. Few reports describe vascular compression as a cause of pseudoachalasia.
Here we present a case of a 84-year-old woman with anorexia, dysphagia and unintentional weight loss initially diagnosed as achalasia. Upon further investigation a rare cause of pseudoachalasia due to vascular compression of the esophagus was found. It could have been overlooked due to the fact that the initial work-out with a barium swallow, manometry and endoscopy was suggestive for primary achalasia.
Particularly in older patients with a manometric diagnosis of achalasia, additional investigation to rule out pseudoachalasia is warranted. Although malignant involvement of the esophagus is the most common cause of pseudoachalasia, benign origins have also been described.
假性贲门失弛缓症是一种罕见的疾病,其临床表现、影像学和测压结果通常与原发性贲门失弛缓症难以区分。它通常与恶性肿瘤有关。很少有报道描述血管压迫是假性贲门失弛缓症的原因。
这里我们介绍一例 84 岁女性,表现为厌食、吞咽困难和不明原因的体重减轻,最初诊断为贲门失弛缓症。进一步检查发现,由于食管血管压迫,导致一种罕见的假性贲门失弛缓症。由于最初的钡餐、测压和内镜检查结果提示原发性贲门失弛缓症,可能会被忽视。
特别是对于有贲门失弛缓症测压诊断的老年患者,需要进一步检查以排除假性贲门失弛缓症。虽然食管恶性受累是假性贲门失弛缓症最常见的原因,但也有良性起源的报道。