Endocrinology and Nutrition Department, Hospital Regional Universitario de Málaga/Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Madrid, Spain.
Pneumology Department, Hospital Regional Universitario de Málaga/Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.
Arch Bronconeumol (Engl Ed). 2021 Mar;57(3):179-185. doi: 10.1016/j.arbres.2020.01.009. Epub 2020 Mar 3.
There are no previous studies aimed at assessing the validity of the screening scales for depression and anxiety in adult patients with bronchiectasis.
To analyze the psychometric properties of Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory (BDI) and Hamilton Anxiety Scale and to evaluate the concordance for the diagnosis of depression and anxiety between these screening scales and the structured clinical interview in adult patients with bronchiectasis.
Cross sectional study. 52 patients with bronchiectasis completed HADS, BDI and Hamilton Anxiety Scale; afterwards, were individually interviewed by a mental health care professional using the structured Mini International Neuropsychiatric Interview (MINI), which evaluates for depression and anxiety according to DSM-IV criteria.
Based on MINI, 18 subjects (34.6%) had a diagnosis of depression and 25 (48.1%) had anxiety. Optimal cut-off values to detect depression were ≥9 for the HADS-D (sensitivity 0.833, specificity 0.971, AUC 0.962 [95% CI 0.918-1]), and 17 for BDI (sensitivity 0.889, specificity 0.912, AUC 0.978 [95% CI 0.945-1]). Optimal cut-off values to detect anxiety were ≥4 for the HADS-A (sensitivity 0.960, specificity 0.593, AUC 0.833 [95% CI 0.723-0.943]), and 17 for Hamilton Anxiety Scale (sensitivity 0.800, specificity 0.852, AUC 0.876 [95% CI 0.781-0.970]).
The self-rating screening scales HADS, BDI and Hamilton Anxiety Scale are reliable tools to screen for depression and anxiety in adult patients with bronchiectasis. However, the use of specific cut-off values may improve the diagnostic accuracy of the previous scales in this specific group of patients.
目前尚无研究旨在评估用于支气管扩张症成年患者的抑郁和焦虑筛查量表的效度。
分析医院焦虑和抑郁量表（HADS）、贝克抑郁量表（BDI）和汉密尔顿焦虑量表的心理测量特性，并评估这些筛查量表与支气管扩张症成年患者的结构化临床访谈在诊断抑郁和焦虑方面的一致性。
横断面研究。52 名支气管扩张症患者完成了 HADS、BDI 和汉密尔顿焦虑量表；之后，由心理健康护理专业人员使用结构化的迷你国际神经精神访谈（MINI）进行个体访谈，该访谈根据 DSM-IV 标准评估抑郁和焦虑。
根据 MINI，18 名患者（34.6%）被诊断为抑郁，25 名患者（48.1%）患有焦虑。用于检测抑郁的最佳截断值为 HADS-D≥9（敏感性 0.833，特异性 0.971，AUC 0.962 [95%CI 0.918-1]），BDI 为 17（敏感性 0.889，特异性 0.912，AUC 0.978 [95%CI 0.945-1]）。用于检测焦虑的最佳截断值为 HADS-A≥4（敏感性 0.960，特异性 0.593，AUC 0.833 [95%CI 0.723-0.943]），Hamilton 焦虑量表为 17（敏感性 0.800，特异性 0.852，AUC 0.876 [95%CI 0.781-0.970]）。
自评筛查量表 HADS、BDI 和汉密尔顿焦虑量表是筛查支气管扩张症成年患者抑郁和焦虑的可靠工具。然而，使用特定的截断值可能会提高这些量表在这一特定患者群体中的诊断准确性。
