Division of Cardiology, "Città della Salute e della Scienza" Hospital, University of Turin, Turin, Italy.
Department of Radiology and Experimental Imaging Centre, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Can J Cardiol. 2020 Apr;36(4):589.e1-589.e4. doi: 10.1016/j.cjca.2019.10.030. Epub 2019 Nov 1.
The coronary sinus Reducer represents a novel therapeutic option with established safety and clinical benefit in the treatment of patients with refractory angina, possibly achieved by enhancing perfusion of myocardial ischemic territories. We report the first case providing insight on how improved perfusion might translate into improved myocardial function as assessed by cardiac magnetic resonance strain imaging, thus suggesting a physiological rationale to test coronary sinus Reducer in the setting of ischemic cardiomyopathy with reduced ejection fraction and adverse remodelling.
冠状窦缩窄器为治疗难治性心绞痛提供了一种新的治疗选择，其安全性和临床获益已得到证实，可能是通过增强心肌缺血部位的灌注来实现的。我们报告了首例病例，该病例深入探讨了灌注改善如何通过心脏磁共振应变成像评估心肌功能，从而为在射血分数降低和不良重构的缺血性心肌病患者中测试冠状窦缩窄器提供了生理依据。
