帕金森病性障碍中的中枢听觉处理：一项系统综述。
Central auditory processing in parkinsonian disorders: A systematic review.
作者信息
De Groote Evelien, De Keyser Kim, Bockstael Annelies, Botteldooren Dick, Santens Patrick, De Letter Miet
机构信息
Department of Rehabilitation Sciences, Ghent University, C. Heymanslaan 10, B-9000, Ghent, Belgium.
Department of Rehabilitation Sciences, Ghent University, C. Heymanslaan 10, B-9000, Ghent, Belgium.
出版信息
Neurosci Biobehav Rev. 2020 Jun;113:111-132. doi: 10.1016/j.neubiorev.2020.03.001. Epub 2020 Mar 4.
Altered auditory processing has been increasingly recognized as a non-motor feature in parkinsonian disorders. This systematic review provides an overview of behavioral and electrophysiological literature on central auditory processing in patients with Parkinson's disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). A systematic database search was conducted and yielded 88 studies that met the intelligibility criteria. The collected data revealed distinct impairments in a range of central auditory processes in PD, including altered deviance detection of basic auditory features, auditory brainstem processing, auditory gating and selective auditory attention. In contrast to PD, literature on central auditory processing in atypical parkinsonian disorders was relatively scarce, but provided some evidence for impaired central auditory processing in MSA and PSP. The interpretation of these findings is discussed and suggestions for further research are offered.
听觉处理改变已越来越被认为是帕金森氏症中的一种非运动特征。本系统综述概述了关于帕金森病（PD）、多系统萎缩（MSA）和进行性核上性麻痹（PSP）患者中枢听觉处理的行为学和电生理学文献。进行了系统的数据库检索，得到88项符合纳入标准的研究。收集的数据显示，PD患者在一系列中枢听觉过程中存在明显损害，包括基本听觉特征的偏差检测改变、听觉脑干处理、听觉门控和选择性听觉注意。与PD不同，关于非典型帕金森氏症中枢听觉处理的文献相对较少，但为MSA和PSP患者中枢听觉处理受损提供了一些证据。本文讨论了这些发现的解读，并提出了进一步研究的建议。
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