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[囊性纤维化与妊娠:结局、预后因素及产科管理]

[Cystic fibrosis and pregnancy: Outcome, prognostic factors and obstetrical management].

作者信息

Fijean A-L, Chamagne M, Billon Y, Morel O, Dahlhoff S

机构信息

Service d'obstétrique, maternité régionale du CHRU de Nancy, 10, rue du Dr Heydenreich, 54000 Nancy, France.

Service d'obstétrique, maternité régionale du CHRU de Nancy, 10, rue du Dr Heydenreich, 54000 Nancy, France.

出版信息

Gynecol Obstet Fertil Senol. 2020 May;48(5):428-435. doi: 10.1016/j.gofs.2020.02.014. Epub 2020 Mar 4.

Abstract

As a result of improvements in life expectancy and therapies, increasing numbers of patients with cystic fibrosis become pregnant. The first studies were pessimistic and report adverse outcomes on the fetus and the mother. In the recent publications, long-term outcome for women with cystic fibrosis does not appear to be negatively impacted by pregnancy. Furthermore, the number of women successfully completing pregnancy continues to rise. The aim of this review is to assess the outcome of pregnancy in women with cystic fibrosis and the impact of pregnancy on the disease. It is hoped it will improve the counseling for pregnant women with cystic fibrosis and their obstetrical management.

摘要

由于预期寿命和治疗方法的改善,越来越多的囊性纤维化患者怀孕。最初的研究结果并不乐观,报告显示对胎儿和母亲都有不良后果。在最近的出版物中,囊性纤维化女性的长期妊娠结局似乎并未受到怀孕的负面影响。此外,成功完成妊娠的女性数量持续增加。本综述的目的是评估囊性纤维化女性的妊娠结局以及怀孕对该疾病的影响。希望这将改善对患有囊性纤维化的孕妇的咨询服务及其产科管理。

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