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18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在炎症性肠病中的应用:前景如何?

FDG-PET/CT in Inflammatory Bowel Disease: Is There a Future?

作者信息

Brodersen Jacob Broder, Hess Søren

机构信息

Department of Gastroenterology, Hospital of Southwest Jutland, Finsensgade 35, Esbjerg Dk-6700, Denmark.

Department of Radiology and Nuclear Medicine, Hospital of Southwest Jutland, Finsensgade 35, Esbjerg Dk-6700, Denmark; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.

出版信息

PET Clin. 2020 Apr;15(2):153-162. doi: 10.1016/j.cpet.2019.11.006.

DOI:10.1016/j.cpet.2019.11.006
PMID:32145886
Abstract

FDG-PET/CT has potential in inflammatory bowel disease. The literature generally presents good sensitivity and specificity in various settings. At present, the most promising roles are assessment of early treatment response and stricture characterization, whereas general use in the initial diagnostic workup should be reserved for equivocal cases for the time being. However, it is challenging to image the moving and physiologically active bowel with FDG, and available literature is far from ideal. Thus, several issues remain unclarified, and further data are needed to make firm conclusions on the role of FDG and PET/CT in inflammatory bowel disease.

摘要

氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)在炎症性肠病中具有应用潜力。文献表明,在各种情况下,其通常具有良好的敏感性和特异性。目前,最有前景的作用是评估早期治疗反应和对狭窄进行特征描述,而目前在初始诊断检查中的常规应用应暂时保留给诊断不明确的病例。然而,使用FDG对蠕动且具有生理活性的肠道进行成像具有挑战性,现有文献也远非理想。因此,仍有几个问题尚未阐明,需要更多数据才能就FDG和PET/CT在炎症性肠病中的作用得出确凿结论。

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