Spechler Stuart Jon
Division of Gastroenterology, Center for Esophageal Diseases, Baylor University Medical Center at Dallas, The Center for Esophageal Research, Baylor Scott & White Research Institute, 3500 Gaston Avenue, 2 Hoblitzelle, Suite 250, Dallas, TX 75246, USA.
Gastrointest Endosc Clin N Am. 2020 Apr;30(2):343-359. doi: 10.1016/j.giec.2019.12.003. Epub 2020 Jan 22.
This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal biopsy, esophageal manometry, and esophageal multichannel intraluminal impedance-pH monitoring. The report provides an approach to patient management that depends on the underlying mechanism identified by this systematic evaluation.
本报告讨论了难治性胃食管反流病（GERD）和功能性烧心可能的潜在机制，以及如何通过系统评估来区分这些机制，该评估包括详细的病史、食管活检内镜检查、食管测压以及食管多通道腔内阻抗-pH监测。本报告提供了一种患者管理方法，该方法取决于通过这种系统评估所确定的潜在机制。
