Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Neurological Surgery, Weill Cornell Medical College, 525 E. 68th St, New York, NY 10065, USA.
Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Neurological Surgery, Weill Cornell Medical College, 525 E. 68th St, New York, NY 10065, USA.
Neurosurg Clin N Am. 2020 Apr;31(2):237-249. doi: 10.1016/j.nec.2019.12.004. Epub 2020 Jan 31.
Intramedullary spinal cord tumors (IMSCT) comprise a rare subset of CNS tumors that have distinct management strategies based on histopathology. These tumors often present challenges in regards to optimal timing for surgery, invasiveness, and recurrence. Advances in microsurgical techniques and technological adjuncts have improved extent of resection and outcomes with IMSCT. Furthermore, adjuvant therapies including targeted immunotherapies and image-guided radiation therapy have witnessed rapid development over the past decade, further improving survival for many of these patients. In this review, we provide an overview of types, epidemiology, imaging characteristics, surgical management strategies, and future areas of research for IMSCT.
脊髓髓内肿瘤（IMSCT）是中枢神经系统肿瘤的一个罕见亚型，其基于组织病理学具有独特的治疗策略。这些肿瘤在手术时机、侵袭性和复发方面常常存在挑战。显微外科技术和技术辅助手段的进步提高了 IMSCT 的切除范围和治疗效果。此外，辅助治疗方法，包括靶向免疫治疗和图像引导放射治疗，在过去十年中得到了快速发展，进一步提高了许多患者的生存率。在这篇综述中，我们提供了 IMSCT 的类型、流行病学、影像学特征、手术治疗策略以及未来研究领域的概述。
