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脊髓外科手术的演进:历史、人物、器械和结果。

The evolution of spinal cord surgery: history, people, instruments, and results.

机构信息

Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, USA.

Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.

出版信息

Childs Nerv Syst. 2023 Oct;39(10):2687-2700. doi: 10.1007/s00381-023-06128-3. Epub 2023 Sep 2.

Abstract

INTRODUCTION

Spinal cord surgery has and always will be a challenging operation with satisfying results, but also with potentially devastating results. Over the last century, there has been an evolution in the way we perceive and conduct spinal cord surgery. The phenomenal evolution in technology from the very first x-ray pictures helps to localize the spinal pathology through the use of high-resolution MRI and ultrasonography that allows for high precision surgery with relatively minimal exposure.

METHODS

The advancements in the surgical technique and the utilization of neuromonitoring allow for maximal safe resection of these delicate and intricate tumors. We also are beginning to understand the biology of spinal cord tumors and vascular lesions, as in the recent 2021 WHO classification which identifies specific entities such as spinal ependymomas, MYCN-amplified, as separate entity from the other subtypes of ependymomas. Surgeons have also accepted the importance of maximal safe resection for most of the spinal cord pathologies rather than just performing biopsy and adjuvant treatment.

CONCLUSION

There have been significant advances since the first resection of an intramedullary tumor including diagnosis, imaging, and surgical technique for children. These advances have improved the prognosis and outcome in these children.

摘要

简介

脊髓手术一直是一项具有挑战性的手术,既能带来满意的效果,也可能带来灾难性的后果。在上个世纪,我们对脊髓手术的认识和实施方式发生了演变。从最初的 X 光片开始,技术就经历了惊人的发展,有助于通过使用高分辨率 MRI 和超声检查来定位脊髓病理,从而实现高精度手术,同时最大限度地减少暴露。

方法

手术技术的进步和神经监测的应用,使这些精细而复杂的肿瘤能够进行最大安全切除。我们也开始了解脊髓肿瘤和血管病变的生物学特性,例如在 2021 年 WHO 分类中,将脊髓室管膜瘤、MYCN 扩增等特定实体识别为与其他室管膜瘤亚型不同的实体。外科医生也接受了对大多数脊髓病变进行最大安全切除的重要性,而不仅仅是进行活检和辅助治疗。

结论

自第一次切除髓内肿瘤以来,包括儿童的诊断、成像和手术技术在内,已经取得了重大进展。这些进展改善了这些儿童的预后和结果。

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