Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Building, Room 3.550, 55 Fruit Street, Boston, MA 02114, USA.
Division of Spine Surgery, Vancouver General Hospital and the University of British Columbia, Blusson Spinal Cord Center, 6th Floor, 818 West 10th Avenue, Vancouver, British Columbia V5Z 1M9, Canada.
Neurosurg Clin N Am. 2020 Apr;31(2):251-261. doi: 10.1016/j.nec.2019.11.007. Epub 2020 Jan 16.
Chordomas are rare tumors of the axial skeleton whose slow growth belies a relentless tumor with a propensity for recurrence and late metastasis. Local control remains an issue with chordoma in spite of aggressive operative management. High local failure rates have led to the exploration of alternative methods of treatment. Radiation continues to gain acceptance as an adjuvant to surgery and, in some cases, as a standalone treatment. However, the use of radiation remains controversial, and operative management remains the standard of care in spite of relatively high morbidity.
脊索瘤是一种罕见的轴性骨骼肿瘤，其缓慢的生长速度掩盖了一种具有复发和晚期转移倾向的无情肿瘤。尽管采用了积极的手术治疗，但脊索瘤的局部控制仍然是一个问题。高局部失败率导致人们探索替代治疗方法。放疗作为手术的辅助治疗手段，在某些情况下作为独立治疗手段，已逐渐被人们接受。然而，放疗的应用仍存在争议，尽管手术治疗的发病率相对较高，但它仍然是治疗的标准。
