Department of Pediatrics, Gemeinschaftskrankenhaus Herdecke, Germany; Professorship for integrative Pediatrics, Witten/Herdecke University, Faculty of Health, Germany.
Department of Psychology, Chair of Research Methodology and Statistics in Psychology, Witten/Herdecke University, Germany.
Complement Ther Med. 2020 Mar;49:102217. doi: 10.1016/j.ctim.2019.102217. Epub 2019 Oct 19.
Our review summarizes published literature of complementary and alternative medicine (CAM) used for the treatment of acute bronchitis in children.
Acute bronchitis is one of the most frequent pediatric diseases and has high prevalence for in- and outpatient care. Acute bronchitis is mainly a viral-caused infection, but a high and inappropriate use of antibiotics has been demonstrated in many countries. As CAM therapies might reduce the use of antibiotics and can complement conventional therapies in children, they could be an appropriate treatment option.
A systematic literature search was conducted using general and complementary and alternative medicine (CAM)-specific databases. A search term including 65 CAM-associated definitions was applied.
Literature search revealed 309 articles, whereby 18 articles hit search criteria. These clinical trials were subgrouped into the categories herbal medicine, anthroposophic medicine and homeopathy. The most often studied approaches are herbal remedies, in particular the Pelargonium sidoides extract, EPs® 7630. Its efficacy was demonstrated in three placebo-controlled trials and two observational studies. Anthroposophic approaches (mainly ribwort-containing remedies) were investigated in two controlled trials and three observational studies. Two studies were found investigating the homeopathic remedies Monapax® and Droperteel®.
Study results indicate a favorable effect of investigated CAM approaches. However, only three of 18 studies were randomized controlled trials (RCTs), so a reliable statement on effectiveness was not possible and further RCTs are indispensable.
本综述总结了已发表的关于补充和替代医学（CAM）用于治疗儿童急性支气管炎的文献。
急性支气管炎是儿童最常见的疾病之一，在门诊和住院治疗中发病率很高。急性支气管炎主要是由病毒引起的感染，但在许多国家都存在高且不适当的抗生素使用情况。由于 CAM 疗法可能减少抗生素的使用，并能为儿童提供常规治疗的补充，因此它们可能是一种合适的治疗选择。
使用一般和补充与替代医学（CAM）特定数据库进行了系统的文献检索。应用了一个包含 65 个 CAM 相关定义的搜索术语。
文献搜索共发现 309 篇文章，其中 18 篇符合搜索标准。这些临床试验被分为草药医学、人智学医学和顺势疗法三个类别。研究最多的方法是草药疗法，特别是 Pelargonium sidoides 提取物 EPs® 7630。三项安慰剂对照试验和两项观察性研究证明了其疗效。两项研究调查了含缬草的顺势疗法药物 Monapax®和 Droperteel®。
研究结果表明，所调查的 CAM 方法具有良好的效果。然而，在 18 项研究中只有 3 项是随机对照试验（RCTs），因此无法对有效性做出可靠的结论，需要进一步的 RCTs。
