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髋关节或膝关节部分翻修术中阳性术中培养物的流行率和影响。

Prevalence and Impact of Positive Intraoperative Cultures in Partial Hip or Knee Revision.

机构信息

Department of Orthopedics and Trauma Surgery, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.

Department of Infectious Diseases, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.

出版信息

J Arthroplasty. 2020 Jul;35(7):1912-1916. doi: 10.1016/j.arth.2020.02.025. Epub 2020 Feb 18.

Abstract

BACKGROUND

Our aim is to investigate the impact of unexpected positive cultures on the outcome of partial prosthetic revisions.

METHODS

Data regarding patients who underwent a partial hip or knee revision from 2003 and 2012 with the preoperative diagnosis of aseptic loosening was retrospectively reviewed. The protocol of revision included at least 3 intraoperative cultures. Failure was defined as the need for re-revision due to aseptic or septic loosening at 5 years.

RESULTS

A total of 99 hip and 46 knee partial revisions were included. All cases had at least 5 years of follow-up. Ninety-seven cases (66.9%) had all cultures negative, 35 (24.1%) a single positive culture and 13 (9.0%) ≥2 positive cultures for the same microorganism. The median time from primary arthroplasty to partial revision was significantly shorter for patients with ≥2 positive cultures (26 months) than in those with all cultures negative (48 months) or with a single positive culture (51 months). Partial revisions performed within the first 5 years of implantation had a higher 5-year re-revision rate. The presence of a single positive culture during the partial exchange was not associated with a higher re-revision rate (2 of 35, 5.7%) than in those with negative cultures (3 of 97, 3.1%). On the contrary, re-revision rate was significantly higher in cases with ≥2 positive cultures (3 of 13, 23.1%) than in those with negative cultures (P = .02).

CONCLUSION

Partial revisions performed within the first 5 years from implantation and ≥2 intraoperative positive cultures were associated with a higher re-revision risk at 5 years.

摘要

背景

本研究旨在探讨意外阳性培养对部分假体翻修结局的影响。

方法

回顾性分析了 2003 年至 2012 年期间因无菌性松动而行髋关节或膝关节部分翻修的患者资料。翻修方案包括至少 3 次术中培养。术后 5 年时因无菌性或感染性松动而需再次翻修定义为失败。

结果

共纳入 99 例髋关节和 46 例膝关节部分翻修。所有病例均随访 5 年以上。97 例(66.9%)所有培养均为阴性,35 例(24.1%)仅 1 次培养阳性,13 例(9.0%)同一种微生物≥2 次培养阳性。与所有培养阴性(48 个月)或仅 1 次培养阳性(51 个月)的患者相比,≥2 次培养阳性(26 个月)的患者初次关节置换至部分翻修的中位时间明显缩短。初次翻修后 5 年内进行的部分翻修 5 年再翻修率更高。在部分翻修时仅有 1 次培养阳性与所有培养阴性(3 例中有 2 例,5.7%)相比,再翻修率(3 例中有 2 例,5.7%)并没有更高。相反,与所有培养阴性(3 例中有 1 例,3.1%)相比,≥2 次培养阳性(3 例中有 3 例,23.1%)的病例再翻修率明显更高(P =.02)。

结论

初次翻修后 5 年内进行的部分翻修和≥2 次术中阳性培养与术后 5 年时再翻修风险增加相关。

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