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双通道内窥镜脊柱手术与显微镜减压治疗腰椎狭窄症:系统评价和荟萃分析。

Biportal Endoscopic Spinal Surgery versus Microscopic Decompression for Lumbar Spinal Stenosis: A Systematic Review and Meta-Analysis.

机构信息

Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia.

Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia.

出版信息

World Neurosurg. 2020 Jun;138:e450-e458. doi: 10.1016/j.wneu.2020.02.151. Epub 2020 Mar 5.

Abstract

OBJECTIVE

Recent studies have shown that the clinical outcome in patients treated with the unilateral biportal endoscopic technique, also known as biportal endoscopic spinal surgery (BESS) unilateral laminotomy bilateral decompression (ULBD) in the context of this study, is more favorable compared with those treated with microscopic ULBD. In this systematic review and meta-analysis, we assess the latest evidence on the use of BESS ULBD compared with microscopic ULBD in patients with lumbar spinal stenosis.

METHODS

We performed a systematic literature search of studies that compared BESS and microscopic ULBD from several databases.

RESULTS

There were 383 patients from 5 unique studies. Meta-analysis of visual analog scale score for low back pain showed no significant difference at baseline (P = 0.49), at 2-3 months (P = 0.69), and at the final follow-up (P = 0.26). There was no significant difference in visual analog scale score for leg pain and Oswestry Disability Index between the groups preoperatively (P = 0.76 and P = 0.95), at 2-3 months (P = 0.46 and P = 0.92), and at the final follow-up (P = 0.88 and P = 0.58). The mean operation time was similar in the BESS and microsurgery groups (P = 0.36). The BESS group was associated with shorter length of stay (mean difference -2.60 days [-3.39, -1.81]; P < 0.001; I = 65%). Complications were similar in both groups (P = 0.26). Individual studies have shown that BESS was associated with early ambulation and less need for opioids.

CONCLUSIONS

Current evidence shows a lack of significant differences in terms of efficacy and safety between BESS and microsurgery. Further studies are required before drawing a definite conclusion.

摘要

目的

最近的研究表明,与接受单侧微创 ULBD 治疗的患者相比,接受双侧经皮内镜技术(也称为双边内窥镜脊柱手术(BESS)单侧椎板切除术双侧减压术(ULBD)治疗的患者的临床结果更为有利。在这项系统评价和荟萃分析中,我们评估了在腰椎管狭窄症患者中使用 BESS ULBD 与显微镜 ULBD 的最新证据。

方法

我们从多个数据库中对比较 BESS 和显微镜 ULBD 的研究进行了系统的文献检索。

结果

有 5 项独特研究中的 383 名患者。视觉模拟量表评分的腰痛的荟萃分析显示基线时无显著差异(P=0.49),2-3 个月时(P=0.69)和最终随访时(P=0.26)。组间术前腿痛和 Oswestry 残疾指数的视觉模拟量表评分无显著差异(P=0.76 和 P=0.95),2-3 个月时(P=0.46 和 P=0.92),以及最终随访时(P=0.88 和 P=0.58)。BESS 组和微创手术组的平均手术时间相似(P=0.36)。BESS 组的住院时间较短(平均差-2.60 天[-3.39,-1.81];P<0.001;I=65%)。两组的并发症相似(P=0.26)。个别研究表明,BESS 与早期活动和较少需要阿片类药物有关。

结论

目前的证据表明,在疗效和安全性方面,BESS 与显微镜手术之间没有显著差异。在得出明确结论之前,需要进一步研究。

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