网络药理学在中医药研究中的应用
Applications of Network Pharmacology in Traditional Chinese Medicine Research.
作者信息
Zhou Zhuchen, Chen Bing, Chen Simiao, Lin Minqiu, Chen Ying, Jin Shan, Chen Weiyan, Zhang Yuyan
机构信息
School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
School of Basic Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
出版信息
Evid Based Complement Alternat Med. 2020 Feb 14;2020:1646905. doi: 10.1155/2020/1646905. eCollection 2020.
Abstract
Human diseases, especially infectious ones, have been evolving constantly. However, their treatment strategies are not developing quickly. Some diseases are caused by a variety of factors with very complex pathologies, and the use of a single drug cannot solve these problems. Traditional Chinese Medicine (TCM) medication is a unique treatment method in China. TCM formulae contain multiple herbs with multitarget, multichannel, and multilink characteristics. In recent years, with the flourishing development of network pharmacology, a new method for searching therapeutic drugs has emerged. The multitarget action in network pharmacology is consistent with the complex mechanisms of disease and drug action. Using network pharmacology to understand TCM is an emerging trend.
摘要
人类疾病，尤其是传染病，一直在不断演变。然而，它们的治疗策略却没有快速发展。有些疾病是由多种因素引起的，病理非常复杂，使用单一药物无法解决这些问题。中药是中国独特的治疗方法。中药方剂包含多种具有多靶点、多途径和多环节特点的草药。近年来，随着网络药理学的蓬勃发展，出现了一种寻找治疗药物的新方法。网络药理学中的多靶点作用与疾病和药物作用的复杂机制相一致。利用网络药理学来理解中药是一个新兴趋势。
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