Huang Ruina, Huang Yunxuan, Huang Ruijia, Huang Shaofen, Wang Xiaojun, Yu Xiaojiang, Xu Danghan, Chen Xinghua
The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Evid Based Complement Alternat Med. 2020 Feb 11;2020:5816717. doi: 10.1155/2020/5816717. eCollection 2020.
Cervical spondylosis (CS) refers to the degenerative changes in the cervical spinal column, which affect the majority of middle-aged and elderly people. Thunder-fire moxibustion originated from thunder-fire miraculous needle, which has been applied widely for treating pain syndromes for thousands of years. The aim of our research is to provide evidence to assess the efficacy and safety of thunder-fire moxibustion in treating CS. Retrieved literature databases included Cochrane Library, MEDLINE, Web of Science, EBSCO, EBASE, Springer, PubMed, WFDP, CNKI, VIP, and CBM. The period of retrieval was from the establishment of the database to December 2018. Randomized controlled trials which compared thunder-fire moxibustion and other therapies in CS were included. The quality of inclusive trials was accessed though a Cochrane risk of bias tool. According to the test results of heterogeneity, a random effect model or fixed effect model was used to analyze the data.
Meta-analysis was conducted for the total effective rate of thunder-fire moxibustion, traditional Chinese medicine syndrome score, pain score, satisfaction score, and score of the symptoms and functional rehabilitation of cervical vertigo. The analysis results were as follows: compared with other therapies, the efficacy of thunder-fire moxibustion was statistically significant, total effective rate increased (OR = 2.48; 95% CI [1.80, 3.41]; < 0.00001), traditional Chinese medicine syndrome score decreased (SMD = -3.05; 95% CI[-4.18, -1.93]; < 0.00001), traditional Chinese medicine syndrome score decreased (SMD = -3.05; 95% CI[-4.18, -1.93]; < 0.00001), traditional Chinese medicine syndrome score decreased (SMD = -3.05; 95% CI[-4.18, -1.93]; < 0.00001), traditional Chinese medicine syndrome score decreased (SMD = -3.05; 95% CI[-4.18, -1.93]; < 0.00001), traditional Chinese medicine syndrome score decreased (SMD = -3.05; 95% CI[-4.18, -1.93].
Based on the existing evidence, the curative effect and safety of thunder-fire moxibustion on CS were statistically significant. We should interpret the results scrupulously because of the low evidence level. Large-scale, high-quality, rigorous RCTs with long-term follow-up should be performed in the future.
颈椎病（CS）是指颈椎柱的退行性改变，影响着大多数中老年人。雷火灸起源于雷火神针，数千年来一直广泛应用于治疗疼痛综合征。我们研究的目的是为评估雷火灸治疗颈椎病的疗效和安全性提供证据。检索的文献数据库包括考克兰图书馆、医学文献数据库、科学网、EBSCO、EBASE、施普林格、PubMed、WFDP、中国知网、维普资讯和中国生物医学文献数据库。检索期为从数据库建立至2018年12月。纳入比较雷火灸与其他疗法治疗颈椎病的随机对照试验。通过考克兰偏倚风险工具评估纳入试验的质量。根据异质性检验结果，采用随机效应模型或固定效应模型分析数据。
对雷火灸的总有效率、中医证候评分、疼痛评分、满意度评分以及颈性眩晕症状与功能康复评分进行荟萃分析。分析结果如下：与其他疗法相比，雷火灸的疗效具有统计学意义，总有效率提高（OR = 2.48；95%可信区间[1.80, 3.41]；P < 0.00001），中医证候评分降低（标准化均数差 = -3.05；95%可信区间[-4.18, -1.93]；P < 0.00001），中医证候评分降低（标准化均数差 = -3.05；95%可信区间[-4.18, -1.93]；P < 0.00001），中医证候评分降低（标准化均数差 = -3.05；95%可信区间[-4.18, -1.93]；P < 0.00001），中医证候评分降低（标准化均数差 = -3.05；95%可信区间[-4.18, -1.93]；P < 0.00001），中医证候评分降低（标准化均数差 = -3.05；95%可信区间[-4.18, -1.93]。
基于现有证据，雷火灸治疗颈椎病的疗效和安全性具有统计学意义。由于证据水平较低，我们应谨慎解释结果。未来应开展大规模、高质量、严谨的长期随访随机对照试验。
