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使用糖化血红蛋白评估扎里亚阿马杜·贝洛大学教学医院(ABUTH)医护人员中糖尿病前期、糖尿病及相关心血管风险的患病率

Prevalence of Pre-Diabetes, Diabetes and Associated Cardiovascular Risk Amongst Healthcare Workers in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria using Glycated Haemoglobin.

作者信息

Onyemelukwe O U, Mamza A A, Suleiman Y K, Iyanda M A, Bello-Ovosi B, Bansi K I, Adeleye A O, Balarabe H, Ahmed M S, Okpe I O, Bello F, Bakari A G

机构信息

Department of Medicine, Ahmadu Bello University Teaching Hospital, Shika, Zaria, Nigeria.

Department of Medicine,University of Maiduguri Teaching Hospital, Borno, Nigeria.

出版信息

West Afr J Med. 2020 Apr-Jun;37(2):91-99.

PMID:32150625
Abstract

BACKGROUND

There is a global rise in the prevalence of diabetes mellitus and pre-diabetes is a fore-runner to type-2 diabetes. Pre-diabetes is reversible, therefore, measures should be taken to halt or slow down its progression to frank diabetes.

AIM

The study aimed to evaluate the prevalence of pre-diabetes and diabetes amongst staff of ABUTH, Zaria and identify some cardiovascular risks associated with them.

METHODS

A cross-sectional analytical study carried out on 377 healthcare workers who presented at the Medical out-patient department of ABUTH, Zaria in response to an invitation for the 2017 World Diabetes Day free medical screening. HbA1c was assessed via Immunofluorescence method. The difference in HbA1c amongst healthcare workers was determined by One-way Analysis of Variance with Post-hoc Bonferroni test. Cardiovascular risk associations were assessed via Multiple Binary Logistic Regression.

RESULTS

Pre-diabetes and diabetes prevalence were 19.4% and 6.5% respectively. There were 28.6% undiagnosed diabetic healthcare workers. There was no significant (p=0.35) difference in HbA1c between different categories of healthcare workers, however, random blood glucose was significantly (p=0.042) higher in other healthcare workers than doctors. There was a significant (p<0.01) association between systolic hypertension and risk of developing pre-diabetes and diabetes (OR, 4.11, CI 0.98-17.30).

CONCLUSION

There is a high prevalence of pre-diabetes and diabetes amongst healthcare workers in Zaria. The odds of hypertensive healthcare workers developing pre-diabetes and diabetes is high. Efforts should be geared at intensifying health education, increased work physical activity and proper diet.

摘要

背景

全球糖尿病患病率呈上升趋势,而糖尿病前期是2型糖尿病的先兆。糖尿病前期是可逆的,因此应采取措施阻止或减缓其发展为显性糖尿病。

目的

本研究旨在评估扎里亚阿巴斯塔健康科学大学(ABUTH)工作人员中糖尿病前期和糖尿病的患病率,并确定与之相关的一些心血管风险。

方法

对377名医护人员进行了一项横断面分析研究,这些人员应2017年世界糖尿病日免费医疗筛查的邀请,前往扎里亚阿巴斯塔健康科学大学门诊部就诊。通过免疫荧光法评估糖化血红蛋白(HbA1c)。医护人员之间HbA1c的差异通过单因素方差分析和事后邦费罗尼检验确定。通过多元二元逻辑回归评估心血管风险关联。

结果

糖尿病前期和糖尿病的患病率分别为19.4%和6.5%。有28.6%的糖尿病医护人员未被诊断出来。不同类别的医护人员之间HbA1c无显著差异(p = 0.35),然而,其他医护人员的随机血糖显著高于医生(p = 0.042)。收缩期高血压与发生糖尿病前期和糖尿病的风险之间存在显著关联(p < 0.01)(比值比,4.11,可信区间0.98 - 17.30)。

结论

扎里亚的医护人员中糖尿病前期和糖尿病的患病率较高。高血压医护人员患糖尿病前期和糖尿病的几率较高。应努力加强健康教育、增加工作中的体力活动和合理饮食。

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