The Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin 2, Ireland.
The Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin 2, Ireland.
Diabetes Res Clin Pract. 2015 Dec;110(3):241-9. doi: 10.1016/j.diabres.2015.10.015. Epub 2015 Oct 19.
The prevalence of type 2 diabetes and pre-diabetes has increased rapidly in recent decades and this trend will continue as the global population ages. This study investigates the prevalence of, and factors associated with, diagnosed and undiagnosed type 2 diabetes mellitus and pre-diabetes in older adults in Ireland.
Cross-sectional data from 5377 men and women aged 50 and over from Wave 1 of the Irish Longitudinal Study on Ageing (TILDA) was analysed. Diagnosed diabetes was defined using self-reported doctors' diagnosis and medications data. Glycated haemoglobin (HbA1c) analysis was used to identify undiagnosed and pre-diabetes. Age and sex-specific prevalence estimates were generated. Logistic regression was used to investigate the association between diabetes classification and the demographic, health and lifestyle characteristics of the population.
The prevalence of diagnosed and undiagnosed type 2 diabetes was 8.6% (95% confidence interval (CI): 7.6-9.5%) and 0.9% (95% CI: 0.6-1.1%) respectively. Diabetes was more prevalent in men than women and increased with age. The prevalence of pre-diabetes was 5.5% (95% CI: 4.8-6.3%) and increased with age. Diabetes and pre-diabetes were independently associated with male sex, central obesity and a history of hypertension, while undiagnosed diabetes was associated with geographic location and medical costs cover.
Despite high rates of obesity and other undiagnosed health conditions, the prevalence of undiagnosed and pre-diabetes is relatively low in community-dwelling older adults in Ireland. Addressing lifestyle factors in this population may help to further reduce the prevalence of pre-diabetes and improve outcomes for those with a previous diagnosis.
近年来，2 型糖尿病和糖尿病前期的患病率迅速上升，随着全球人口老龄化，这一趋势还将继续。本研究调查了爱尔兰老年人群中诊断和未诊断的 2 型糖尿病和糖尿病前期的患病率及其相关因素。
分析了爱尔兰老龄化纵向研究（TILDA）第 1 波中 5377 名年龄在 50 岁及以上的男性和女性的横断面数据。使用自我报告的医生诊断和药物数据来定义诊断糖尿病。糖化血红蛋白（HbA1c）分析用于确定未诊断和糖尿病前期。生成了按年龄和性别划分的患病率估计值。使用逻辑回归调查了糖尿病分类与人群的人口统计学、健康和生活方式特征之间的关联。
诊断和未诊断的 2 型糖尿病的患病率分别为 8.6%（95%置信区间（CI）：7.6-9.5%）和 0.9%（95%CI：0.6-1.1%）。男性的糖尿病患病率高于女性，且随年龄增长而增加。糖尿病前期的患病率为 5.5%（95%CI：4.8-6.3%），并随年龄增长而增加。糖尿病和糖尿病前期与男性、中心性肥胖和高血压病史独立相关，而未诊断的糖尿病与地理位置和医疗费用覆盖有关。
尽管肥胖率和其他未确诊的健康状况较高，但爱尔兰社区居住的老年人群中未诊断和糖尿病前期的患病率相对较低。在该人群中解决生活方式因素可能有助于进一步降低糖尿病前期的患病率，并改善有既往诊断的人群的预后。
