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[大鼠大脑皮质微循环网络的结构功能模数]

[The structuro-functional modulus of the microcirculatory network of the cerebral cortex in rats].

作者信息

Kilibaeva G S, Demchenko I T, Moskalenko Iu E

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Sep;74(9):1235-42.

PMID:3215330
Abstract

Complex investigation carried out in rats with the aid of polarographic microelectrodes revealed a mosaic distribution of blood supply within a small volume of nerve tissue in resting. The activation of cortical neurons was accompanied by local functional hyperemia and increased level of oxygen available. The hyperemia spread over a 200-300 mu area corresponding to the sides of neuronal columns. The data obtained have shown that the system of the cortex blood circulation and oxygen transport to neural tissues is based on a special microcirculatory module responsible for circulatory-metabolic supply of separate groups of neurons and composed as vertically oriented columns.

摘要

借助极谱微电极在大鼠身上进行的复杂研究揭示,在静息状态下,少量神经组织内的血液供应呈镶嵌分布。皮层神经元的激活伴随着局部功能性充血以及可利用氧水平的升高。充血扩散至与神经元柱侧面相对应的200 - 300微米区域。所获得的数据表明,皮层血液循环和向神经组织输送氧气的系统基于一个特殊的微循环模块,该模块负责为不同组别的神经元提供循环代谢供应,并且由垂直排列的柱体组成。

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