慢性肾脏病患者急性冠状动脉综合征的动脉粥样硬化负担及治疗挑战
Atherosclerosis Burden and Therapeutic Challenges Regarding Acute Coronary Syndromes in Chronic Kidney Disease Patients.
作者信息
Moisi Madalina Ioana, Vesa Cosmin, Rosan Larisa Pantea, Tica Otilia, Ardelean Adriana, Zaha Dana, Burta Ovidiu, Popescu Mircea Ioachim
机构信息
University of Oradea, Faculty of Medicine and Pharmacy, Oradea, Romania.
出版信息
Maedica (Bucur). 2019 Dec;14(4):378-383. doi: 10.26574/maedica.2019.14.4.378.
Abstract
The major cause of death in patients with chronic kidney disease is represented by cardiovascular events. Atherosclerosis is usually initiated by the association of traditional and non-traditional risk factors, and the acute thrombotic complications are more frequent in subjects with reduced glomerular filtration rate. The diagnosis of acute coronary syndromes is challenging due to the increased values of cardiac necrosis enzymes correlated with reduced renal function.
摘要
慢性肾病患者的主要死因是心血管事件。动脉粥样硬化通常由传统和非传统风险因素共同引发，急性血栓并发症在肾小球滤过率降低的患者中更为常见。由于与肾功能降低相关的心脏坏死酶值升高，急性冠脉综合征的诊断具有挑战性。
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