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豆类中的生物活性蛋白质和植物化学物质:预防肥胖和 2 型糖尿病的作用机制。

Bioactive proteins and phytochemicals from legumes: Mechanisms of action preventing obesity and type-2 diabetes.

机构信息

Tecnología de Alimentos, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C, 44270 Guadalajara, Mexico.

Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, IL 61801, United States.

出版信息

Food Res Int. 2020 Apr;130:108905. doi: 10.1016/j.foodres.2019.108905. Epub 2019 Dec 18.

Abstract

The Fabaceae family of plants include a variety of seeds with multiple shapes, sizes, and colors; with a great diversity of bioactive compounds found in legume seeds. Legumes are an excellent source of protein, peptides and phytochemicals which are present in significant amounts. These bioactive compounds have been reported to reduce the risk of developing non-communicable diseases (NCD), such as obesity and type-2 diabetes. In this narrative review, we discuss the biological potential of bioactive compounds found in legumes and the health benefits associated with their consumption as an alternative approach in the management of NCD. Current extraction methods, characteristics of the bioactive compounds, and different in vitro and in vivo studies evaluating the bioactivity of legume bioactives are reviewed and discussed.

摘要

豆科植物家族的植物包括多种形状、大小和颜色的种子;豆类种子中含有多种生物活性化合物。豆类是蛋白质、肽和植物化学物质的极好来源,这些物质的含量都相当高。据报道,这些生物活性化合物可以降低患非传染性疾病(NCD)的风险,如肥胖和 2 型糖尿病。在这篇叙述性评论中,我们讨论了豆类中发现的生物活性化合物的生物学潜力,以及它们作为非传染性疾病管理的替代方法的消费相关的健康益处。本文综述了当前的提取方法、生物活性化合物的特性,以及不同的体外和体内研究评估豆类生物活性的方法。

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