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Inflammasome-more Injury in Cholestasis.

作者信息

Zhao Xiao, Wangensteen Kirk J

机构信息

Division of Digestive Diseases, Department of Medicine, Columbia University, New York, New York.

Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Cell Mol Gastroenterol Hepatol. 2020;9(4):711-712. doi: 10.1016/j.jcmgh.2020.02.004. Epub 2020 Mar 7.

DOI:10.1016/j.jcmgh.2020.02.004
PMID:32156506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7212471/
Abstract
摘要

相似文献

1
Inflammasome-more Injury in Cholestasis.炎症小体——胆汁淤积中更多的损伤
Cell Mol Gastroenterol Hepatol. 2020;9(4):711-712. doi: 10.1016/j.jcmgh.2020.02.004. Epub 2020 Mar 7.
2
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.鹅去氧胆酸激活NLRP3炎性小体并促进胆汁淤积性肝纤维化。
Oncotarget. 2016 Dec 20;7(51):83951-83963. doi: 10.18632/oncotarget.13796.
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A Novel Protective Role for FXR against Inflammasome Activation and Endotoxemia.FXR 在炎症小体激活和内毒素血症中具有新的保护作用。
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Oxid Med Cell Longev. 2019 Nov 18;2019:6565283. doi: 10.1155/2019/6565283. eCollection 2019.
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Severe acute cholestatic hepatitis with prolonged cholestasis and bile-duct injury following atorvastatin therapy: a case report.阿托伐他汀治疗后出现严重急性胆汁淤积性肝炎伴胆汁淤积延长和胆管损伤：一例报告
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Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis.Pipe-3D：一种基于免疫荧光、三维共聚焦成像、重建和形态测量学的管道，用于胆汁淤积中胆管网络分析。
Methods Mol Biol. 2019;1981:25-53. doi: 10.1007/978-1-4939-9420-5_3.

本文引用的文献

1
Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse.在胆汁淤积患者的肝脏中炎症小体被激活，并在胆管结扎小鼠中加重肝损伤。
Cell Mol Gastroenterol Hepatol. 2020;9(4):679-688. doi: 10.1016/j.jcmgh.2019.12.008. Epub 2019 Dec 27.
2
Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study.伐地那非对小鼠胆汁淤积性肝损伤的抗炎作用：一项机制研究。
Cell Physiol Biochem. 2018;47(2):523-534. doi: 10.1159/000489986. Epub 2018 May 23.
3
Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis.法尼醇X受体对NLRP3炎性小体的调节是胆汁淤积相关性脓毒症的基础。
Cell Metab. 2017 Apr 4;25(4):856-867.e5. doi: 10.1016/j.cmet.2017.03.007.
4
Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.胆汁酸通过触发肝细胞特异性炎症反应引发胆汁淤积性肝损伤。
JCI Insight. 2017 Mar 9;2(5):e90780. doi: 10.1172/jci.insight.90780.
5
Inflammasomes as polyvalent cell death platforms.炎症小体作为多价细胞死亡平台。
Cell Mol Life Sci. 2016 Jun;73(11-12):2335-47. doi: 10.1007/s00018-016-2204-3. Epub 2016 Apr 5.
6
Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.胆汁酸在肝细胞中诱导炎症基因：梗阻性胆汁淤积时炎症发生的新机制。
Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23.