一株稻瘟病菌中新型的 Narnavirus

A novel narnavirus from the plant-pathogenic fungus Magnaporthe oryzae.

机构信息

College of Agriculture, Yangtze University, Jingzhou, 434025, Hubei, China.

College of Plant Protection, Hainan University, Haikou, 570228, Hainan, China.

出版信息

Arch Virol. 2020 May;165(5):1235-1240. doi: 10.1007/s00705-020-04586-7. Epub 2020 Mar 10.

DOI:10.1007/s00705-020-04586-7

PMID:32157391

Abstract

A novel mycovirus with the proposed name "Magnaporthe oryzae narnavirus virus 1" (MoNV1), was described in the rice blast fungus Magnaporthe oryzae. The virus has a single-stranded (+ss) RNA genome of 2452 nucleotides, contains a single open reading frame (ORF) predicted to encode an RNA-dependent RNA polymerase (RDRP), and is closely related to some viruses of the genus Narnavirus, family Narnaviridae, including Aspergillus fumigatus narnavirus 1 (AfNV1), Neofusicoccum parvum narnavirus 2 (NpNV2) and Alternaria tenuissima narnavirus 1 (AtNV2). Genome sequence comparisons and phylogenetic analysis suggested that MoNV1 is a new member of the genus Narnavirus. The RDRPs of MoNV1 and some closely related narnaviruses do not contain a typical metal-binding "GDD" motif and catalytic site. Further studies are needed to investigate the replication mechanism of these viruses.

摘要

一种新的真菌病毒，命名为“稻瘟病菌 Narnavirus 病毒 1”（MoNV1），在稻瘟病菌中被发现。该病毒具有单链（+ss）RNA 基因组，长度为 2452 个核苷酸，包含一个单一的开放阅读框（ORF），预测编码 RNA 依赖性 RNA 聚合酶（RDRP），与 Narnavirus 属的一些病毒密切相关，包括烟曲霉 Narnavirus 1（AfNV1）、细极链格孢菌 Narnavirus 2（NpNV2）和细链格孢菌 Narnavirus 1（AtNV2）。基因组序列比较和系统发育分析表明，MoNV1 是 Narnavirus 属的一个新成员。MoNV1 和一些密切相关的 Narnavirus 的 RDRP 不包含典型的金属结合“GDD”基序和催化位点。需要进一步研究来探讨这些病毒的复制机制。