Crespi V, Bogliun G, Delodovici M L, Sanguineti I
Divisione di Neurologia 1., Ospedale San Gerardo, Monza.
Ital J Neurol Sci. 1988 Oct;9(5):459-66. doi: 10.1007/BF02337163.
26 patients with ataxic hemiparesis syndrome (AHS), due to acute ischemic cerebrovascular disease, have been submitted to clinical and electrophysiological evaluation, in order to assess the frequency of sensory disturbances in this condition. Sensory impairment were present in 78% and SEP abnormalities in 54% of the patients, while they were entirely absent in 23% of them. Lesions responsible for AHS, detected by CT scan, were mainly located in the thalamus, capsula interna, subcortical white matter, centro parietal cortex; sensory and SEP changes were more frequent in gross infarct involving the cortex and in smaller infarcts involving the thalamus, less frequent in the lacunar infarcts of the capsula interna and subcortical white matter, relatively rare in patients with CT scan without hypodense lesions. Although a statokinesthesic defect and/or major SEP abnormalities were often present (38% of patients), our findings do not support the view that they are involved in the pathogenesis of the ataxia, which may rather be attributed to a derangement of cerebro-cerebellar and cerebello-cerebral connections.
26例因急性缺血性脑血管病导致共济失调性偏瘫综合征（AHS）的患者接受了临床和电生理评估，以评估该病症中感觉障碍的发生率。78%的患者存在感觉障碍，54%的患者体感诱发电位（SEP）异常，而23%的患者完全没有这些情况。通过CT扫描检测到的导致AHS的病变主要位于丘脑、内囊、皮质下白质、中央顶叶皮质；在累及皮质的大面积梗死和累及丘脑的较小梗死中，感觉和SEP变化更为常见，在内囊和皮质下白质的腔隙性梗死中则较少见，在CT扫描无低密度病变的患者中相对罕见。尽管经常存在静态运动觉缺陷和/或主要的SEP异常（38%的患者），但我们的研究结果并不支持它们参与共济失调发病机制的观点，共济失调可能更多地归因于脑-小脑和小脑-脑连接的紊乱。
