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独居与与他人同住对老年人骨折后死亡率的预测作用。

Living alone vs. living with someone as a predictor of mortality after a bone fracture in older age.

机构信息

Faculty of Sport and Health Sciences and Gerontology Research Center, University of Jyväskylä, Jyväskylä, Finland.

Folkhälsan Research Center, Helsinki, Finland.

出版信息

Aging Clin Exp Res. 2020 Sep;32(9):1697-1705. doi: 10.1007/s40520-020-01511-5. Epub 2020 Mar 9.

Abstract

BACKGROUND

Living alone is a risk factor for health decline in old age, especially when facing adverse events increasing vulnerability.

AIM

We examined whether living alone is associated with higher post-fracture mortality risk.

METHODS

Participants were 190 men and 409 women aged 75 or 80 years at baseline. Subsequent fracture incidence and mortality were followed up for 15 years. Extended Cox regression analysis was used to compare the associations between living arrangements and mortality risk during the first post-fracture year and during the non-fracture time. All participants contributed to the non-fracture state until a fracture occurred or until death/end of follow-up if they did not sustain a fracture. Participants who sustained a fracture during the follow-up returned to the non-fracture state 1 year after the fracture unless they died or were censored due to end of follow-up.

RESULTS

Altogether, 22% of men and 40% of women sustained a fracture. During the first post-fracture year, mortality risk was over threefold compared to non-fracture time but did not differ by living arrangement. In women, living alone was associated with lower mortality risk during non-fracture time, but the association attenuated after adjustment for self-rated health. In men, living alone was associated with increased mortality risk during non-fracture time, although not significantly.

CONCLUSION

The results suggest that living alone is not associated with pronounced mortality risk after a fracture compared to living with someone.

摘要

背景

独居是老年人健康状况下降的一个风险因素,尤其是在面临增加脆弱性的不利事件时。

目的

我们研究了独居是否与更高的骨折后死亡风险相关。

方法

参与者为 190 名男性和 409 名 75 或 80 岁的女性。随后随访了 15 年骨折的发生率和死亡率。使用扩展的 Cox 回归分析比较了不同居住安排与骨折后第一年和非骨折期间死亡率风险之间的关系。所有参与者在骨折发生之前或在未发生骨折的情况下因随访结束而死亡/终止之前,均对非骨折状态做出贡献。在随访期间发生骨折的参与者,在骨折后 1 年内返回非骨折状态,除非他们死亡或因随访结束而被删失。

结果

总共,22%的男性和 40%的女性发生了骨折。与非骨折时期相比,骨折后第一年的死亡率风险增加了三倍以上,但与居住安排无关。在女性中,独居与非骨折时期的死亡率风险降低相关,但在调整自我报告的健康状况后,这种关联减弱。在男性中,独居与非骨折时期的死亡率风险增加相关,但并不显著。

结论

结果表明,与与他人同住相比,独居与骨折后明显的死亡率风险无关。

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