罗威纳犬中，[具体成分1]和/或[具体成分2]叶粉作为糖尿病有前景的临床营养管理工具的降血糖功效。
Hypoglycemic efficacy of and/or leaves powder as a promising clinico-nutritional management tool for diabetes mellitus in Rottweiler dogs.
作者信息
Abdelrahman Noha, El-Banna Ramadan, Arafa Mahmoud M, Hady Maha M
机构信息
Department of Chemistry and Toxicology, Malnutrition Unit, Animal Health Research Institute, Giza, Egypt.
Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
出版信息
Vet World. 2020 Jan;13(1):73-79. doi: 10.14202/vetworld.2020.73-79. Epub 2020 Jan 10.
BACKGROUND AND AIM
This study examined the impact of dietary fortification with rosemary () and/or basil () leaves powder on glycemic status of dogs.
MATERIALS AND METHODS
Forty-five Rottweiler dogs were assigned to five experimental groups and fed an experimentally processed extruded basal diet that was either fortified or not fortified. G1 was fed the basal diet without any fortification (negative control); G2 was consumed the basal diet supplemented with a commercially available synthetic palatant (positive control); G3 was provided with rosemary fortified (at 0.05%) basal diet; G4 was provided with a basil fortified (at 0.05%) basal diet; and G5 was offered a rosemary and basil fortified (each at 0.025%) basal diet.
RESULTS
G4 and G5 exhibited a positive impact on growth performance traits. Dogs in G3, G4, and G5 showed significant decreases in serum glucose levels in comparison to dogs of the control groups (G1 and G2). It was clear that the inclusion level of 0.05% of basil leaves powder showed the greatest hypoglycemic action. Indeed, G4 dogs showed a reduction in blood glucose at a percentage of approximately 31% followed by G5 and G3 groups (16.25% and 14%, respectively). Furthermore, basil leaves inhibited the amylase enzyme activity. Both insulin and cortisol levels in G4 dogs were increased and reduced compared to controls, respectively. In addition, dietary fortification with rosemary and/or basil significantly increased glutathione, superoxide dismutase, and catalase levels, while values for malondialdehyde and lactate dehydrogenase were decreased.
CONCLUSION
It could be concluded that dietary fortification of dog diet with rosemary and/or basil leaves powder at 0.05% separately or 0.025% in combination might be used as promising modulators of blood glucose levels as well as clinico-nutritional management tools for the prevention and control of diabetes mellitus in dogs.
背景与目的
本研究探讨了用迷迭香叶粉和/或罗勒叶粉强化日粮对犬血糖状况的影响。
材料与方法
45只罗威纳犬被分为5个实验组，饲喂经过实验加工的挤压基础日粮，该日粮要么经过强化，要么未经过强化。G1组饲喂未强化的基础日粮（阴性对照）；G2组食用添加了市售合成诱食剂的基础日粮（阳性对照）；G3组饲喂添加了0.05%迷迭香的强化基础日粮；G4组饲喂添加了0.05%罗勒的强化基础日粮；G5组饲喂添加了0.025%迷迭香和0.025%罗勒的强化基础日粮。
结果
G4组和G5组对生长性能指标有积极影响。与对照组（G1组和G2组）的犬相比，G3组、G4组和G5组的犬血清葡萄糖水平显著降低。显然，添加0.05%罗勒叶粉的水平显示出最大的降血糖作用。事实上，G4组犬的血糖降低了约31%，其次是G5组和G3组（分别为16.25%和14%）。此外，罗勒叶抑制淀粉酶活性。与对照组相比，G4组犬的胰岛素水平升高，皮质醇水平降低。此外，用迷迭香和/或罗勒强化日粮显著提高了谷胱甘肽、超氧化物歧化酶和过氧化氢酶水平，而丙二醛和乳酸脱氢酶的值降低。
结论
可以得出结论，在犬粮中分别添加0.05%的迷迭香叶粉和/或罗勒叶粉，或两者组合添加0.025%，可能作为有前景的血糖水平调节剂以及预防和控制犬糖尿病的临床营养管理工具。
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