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植物营养素作为治疗剂。

Phytonutrients as therapeutic agents.

作者信息

Gupta Charu, Prakash Dhan

出版信息

J Complement Integr Med. 2014 Sep;11(3):151-69. doi: 10.1515/jcim-2013-0021.

Abstract

Nutrients present in various foods plays an important role in maintaining the normal functions of the human body. The major nutrients present in foods include carbohydrates, proteins, lipids, vitamins, and minerals. Besides these, there are some bioactive food components known as "phytonutrients" that play an important role in human health. They have tremendous impact on the health care system and may provide medical health benefits including the prevention and/or treatment of disease and various physiological disorders. Phytonutrients play a positive role by maintaining and modulating immune function to prevent specific diseases. Being natural products, they hold a great promise in clinical therapy as they possess no side effects that are usually associated with chemotherapy or radiotherapy. They are also comparatively cheap and thus significantly reduce health care cost. Phytonutrients are the plant nutrients with specific biological activities that support human health. Some of the important bioactive phytonutrients include polyphenols, terpenoids, resveratrol, flavonoids, isoflavonoids, carotenoids, limonoids, glucosinolates, phytoestrogens, phytosterols, anthocyanins, ω-3 fatty acids, and probiotics. They play specific pharmacological effects in human health such as anti-microbial, anti-oxidants, anti-inflammatory, antiallergic, anti-spasmodic, anti-cancer, anti-aging, hepatoprotective, hypolipidemic, neuroprotective, hypotensive, diabetes, osteoporosis, CNS stimulant, analgesic, protection from UVB-induced carcinogenesis, immuno-modulator, and carminative. This mini-review attempts to summarize the major important types of phytonutrients and their role in promoting human health and as therapeutic agents along with the current market trend and commercialization.

摘要

各种食物中所含的营养素在维持人体正常功能方面起着重要作用。食物中的主要营养素包括碳水化合物、蛋白质、脂质、维生素和矿物质。除此之外,还有一些被称为“植物营养素”的生物活性食物成分,它们对人类健康起着重要作用。它们对医疗保健系统有巨大影响,并可能提供医疗健康益处,包括预防和/或治疗疾病及各种生理紊乱。植物营养素通过维持和调节免疫功能来预防特定疾病,从而发挥积极作用。作为天然产物,它们在临床治疗中前景广阔,因为它们没有通常与化疗或放疗相关的副作用。它们相对便宜,因此显著降低了医疗保健成本。植物营养素是具有支持人类健康的特定生物活性的植物性营养素。一些重要的生物活性植物营养素包括多酚、萜类化合物、白藜芦醇、黄酮类化合物、异黄酮类化合物、类胡萝卜素、柠檬苦素、硫代葡萄糖苷、植物雌激素、植物甾醇、花青素、ω-3脂肪酸和益生菌。它们在人类健康中发挥特定的药理作用,如抗菌、抗氧化、抗炎、抗过敏、解痉、抗癌、抗衰老、保肝、降血脂、神经保护、降血压、治疗糖尿病、预防骨质疏松、中枢神经系统刺激、止痛、预防紫外线诱导的致癌作用、免疫调节和驱风。这篇综述试图总结植物营养素的主要重要类型及其在促进人类健康和作为治疗剂方面的作用,以及当前的市场趋势和商业化情况。

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