Zazoulina Julia, Cheung Christopher C, Hurlburt Andrew, Chahal Daljeet, Wong Steve
Division of General Internal Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
CJC Open. 2019 Apr 10;1(4):206-208. doi: 10.1016/j.cjco.2019.04.001. eCollection 2019 Jul.
We present a case of adult-onset Kawasaki disease shock syndrome complicated by coronary aneurysms, in which profound hypotension and reduced left ventricular ejection fraction were treated successfully with intravenous immunoglobulin. The diagnosis of Kawasaki disease shock syndrome should be considered in cases of rapidly developing shock, particularly in young adults with an infectious prodrome, in whom it may be under-recognized. We advocate for early identification to minimize delays in treatment with intravenous immunoglobulin, which reverses left ventricular dysfunction and decreases risk of long-term sequelae such as coronary artery aneurysms.
我们报告一例成人起病的川崎病休克综合征并发冠状动脉瘤的病例,该患者出现严重低血压和左心室射血分数降低,通过静脉注射免疫球蛋白成功治愈。对于迅速发展为休克的病例,尤其是伴有感染前驱症状的年轻成年人,应考虑川崎病休克综合征的诊断,因为该病可能未得到充分认识。我们主张早期识别,以尽量减少静脉注射免疫球蛋白治疗的延迟,这种治疗可逆转左心室功能障碍,并降低冠状动脉瘤等长期后遗症的风险。