使用干细胞治疗视网膜疾病的临床研究：最新进展
Clinical studies using stem cells for treatment of retinal diseases: state of the art.
作者信息
Cotrim Carina Costa, Jorge Rodrigo, Oliveira Maria Carolina de, Pieroni Fabiano, Messias André M Vieira, Siqueira Rubens Camargo
机构信息
Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Department of Internal Medicine Faculty of Medicine of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
出版信息
Arq Bras Oftalmol. 2020 Mar-Apr;83(2):160-167. doi: 10.5935/0004-2749.20200037.
Degenerative retinal diseases such as retinitis pigmentosa, Stargardt's macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to direct or indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effects, and the main clinical trials involving them.
诸如色素性视网膜炎、斯塔加特黄斑营养不良和年龄相关性黄斑变性等退行性视网膜疾病的特征是由于直接或间接的光感受器损伤导致不可逆的视力丧失。目前尚无有效的治疗方法，但干细胞研究已显示出有希望的结果。我们撰写这篇综述的目的是描述正在研究的干细胞类型、它们的作用以及涉及它们的主要临床试验。
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