Takeshima Masahiro, Ishikawa Hiroyasu, Umeta Yoshiaki, Kudoh Mizuki, Umakoshi Akise, Yoshizawa Kazuhisa, Ito Yu, Hosoya Tomoko, Tsutsui Ko, Ohta Hidenobu, Mishima Kazuo
Department of Neuropsychiatry, Akita University Graduate School of Medicine, Akita 010-8543, Japan.
Department of Psychiatry, Omagari City Hospital, Akita 014-0067, Japan.
Neuropsychiatr Dis Treat. 2020 Feb 26;16:579-587. doi: 10.2147/NDT.S243308. eCollection 2020.
While depression has been recognized as a risk factor for venous thromboembolism (VTE), the prevalence of VTE in depressed inpatients has never been investigated. The aim of this study was thus to examine VTE prevalence and factors associated with VTE in depressed inpatients.
We conducted a retrospective cross-sectional study of consecutive depressed inpatients (n = 94) from January 1, 2018, to June 30, 2019, at the psychiatry department of Akita University Hospital. As part of our clinical routine, depressed inpatients were screened for VTE using D-dimer, and patients who screened positive underwent enhanced CT to examine VTE. A variety of data was extracted from medical records, including, amongst others, age, sex, body mass index, diagnoses of psychiatric disorders, total scores on the 17-item Hamilton Depression Rating Scale, duration of current depressive episode, daily dosages of antidepressants and antipsychotics, catatonia, and physical restraint.
VTE was detected in 8.5% of depressed inpatients. There were no significant differences between VTE-positive and VTE-negative inpatients regarding any of the considered factors.
Our analysis shows a VTE prevalence of 8.5% in depressed inpatients, higher than that of 2.3% reported in a previous study in hospitalized patients with psychiatric disorders including depression. This emphasizes the importance of VTE screening for depressive inpatients.
虽然抑郁症已被确认为静脉血栓栓塞症（VTE）的一个风险因素，但从未对抑郁症住院患者中VTE的患病率进行过调查。因此，本研究的目的是检查抑郁症住院患者中VTE的患病率以及与VTE相关的因素。
我们对2018年1月1日至2019年6月30日在秋田大学医院精神科连续收治的抑郁症住院患者（n = 94）进行了一项回顾性横断面研究。作为我们临床常规工作的一部分，使用D-二聚体对抑郁症住院患者进行VTE筛查，筛查呈阳性的患者接受增强CT检查以确定是否存在VTE。从病历中提取了各种数据，包括年龄、性别、体重指数、精神疾病诊断、17项汉密尔顿抑郁量表总分、当前抑郁发作的持续时间、抗抑郁药和抗精神病药的每日剂量、紧张症以及身体约束情况等。
在抑郁症住院患者中，8.5%被检测出患有VTE。在任何所考虑的因素方面，VTE阳性和VTE阴性住院患者之间均无显著差异。
我们的分析显示，抑郁症住院患者中VTE的患病率为8.5%，高于先前一项针对包括抑郁症在内的精神疾病住院患者的研究报告的2.3%。这强调了对抑郁症住院患者进行VTE筛查的重要性。
