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伴淋巴样间质的微结节型胸腺瘤的外科治疗

Surgical treatment of micronodular thymoma with lymphoid stroma.

作者信息

Kang Min Kyun, Kang Do Kyun, Hwang Youn-Ho, Kim Ji Yeon

机构信息

Department of Thoracic and Cardiovascular Surgery Haeundae Paik Hospital, Inje University College of Medicine Busan South Korea.

Department of Pathology Haeundae Paik Hospital, Inje University College of Medicine Busan South Korea.

出版信息

Respirol Case Rep. 2020 Mar 5;8(3):e00548. doi: 10.1002/rcr2.548. eCollection 2020 Apr.

DOI:10.1002/rcr2.548
PMID:32161648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7058891/
Abstract

This case was about a 71-year-old man presented to our clinic for an anterior mediastinal mass found on routine chest computed tomography (CT). CT scan showed a lobulating contoured mass in the anterior mediastinum. A preliminary diagnosis was thymoma. The patient underwent subxiphoid uniportal video-assisted thoracoscopic surgery for the extended thymectomy and complete excision of the tumour. The pathological examination showed a micronodular thymoma with lymphoid stroma (MTWLS). In conclusion, this report described an extremely rare tumour, MTWLS, and MTWLS might be considered in the differential diagnosis of mediastinal tumour, especially thymoma.

摘要

该病例为一名71岁男性,因常规胸部计算机断层扫描(CT)发现前纵隔肿块前来我院就诊。CT扫描显示前纵隔有一个分叶状肿块。初步诊断为胸腺瘤。患者接受了剑突下单孔电视辅助胸腔镜手术,以扩大胸腺切除术并完整切除肿瘤。病理检查显示为微结节性胸腺瘤伴淋巴样间质(MTWLS)。总之,本报告描述了一种极为罕见的肿瘤MTWLS,在纵隔肿瘤尤其是胸腺瘤的鉴别诊断中可能需要考虑MTWLS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b92/7058891/7a7e0f75b44d/RCR2-8-e00548-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b92/7058891/385dc692c972/RCR2-8-e00548-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b92/7058891/7a7e0f75b44d/RCR2-8-e00548-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b92/7058891/385dc692c972/RCR2-8-e00548-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b92/7058891/7a7e0f75b44d/RCR2-8-e00548-g002.jpg

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本文引用的文献

1
Micronodular thymoma with lymphoid stroma diagnosed 10 years after the first operation: a case report.首次手术后10年诊断出的微结节型胸腺瘤伴淋巴样间质:一例报告
J Med Case Rep. 2019 Mar 16;13(1):69. doi: 10.1186/s13256-019-2006-y.
2
Micronodular thymoma with lymphoid stroma: Two cases, one in a multilocular thymic cyst, and literature review.微结节性胸腺瘤伴淋巴间质:两例报告,一例发生于多房性胸腺囊肿内,并复习文献。
Thorac Cancer. 2017 Nov;8(6):734-740. doi: 10.1111/1759-7714.12517. Epub 2017 Sep 20.
3
Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart.
《2015年世界卫生组织肺、胸膜、胸腺和心脏肿瘤分类》简介
J Thorac Oncol. 2015 Sep;10(9):1240-1242. doi: 10.1097/JTO.0000000000000663.
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The spectrum of micronodular thymic epithelial tumours with lymphoid B-cell hyperplasia.伴有淋巴B细胞增生的微结节性胸腺上皮肿瘤谱系
Histopathology. 2001 Jun;38(6):519-27. doi: 10.1046/j.1365-2559.2001.01133.x.
5
Multilocular thymic cyst: an acquired reactive process. Study of 18 cases.多房性胸腺囊肿:一种后天性反应性病变。18例病例研究
Am J Surg Pathol. 1991 Apr;15(4):388-98.