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甲型流感病毒感染并发勒米尔综合征。

Lemierre's syndrome complicating influenza A virus infection.

作者信息

Yanagi Hidetaka, Ozawa Hideki

机构信息

Department of Internal Medicine Tokai University School of Medicine Isehara City Kanagawa Japan.

出版信息

J Gen Fam Med. 2019 Dec 13;21(2):18-20. doi: 10.1002/jgf2.293. eCollection 2020 Mar.

DOI:10.1002/jgf2.293
PMID:32161697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7060288/
Abstract

We report a 24-year-old previously healthy woman with Lemierre's syndrome following influenza A virus infection. One week after influenza A was diagnosed by rapid antigen test and treated by oseltamivir, she developed multiple cavitary lung lesions, and a left internal jugular vein thrombosis. The blood culture grew Fusobacterium necrophorum. We administered ampicillin-sulbactam and unfractionated heparin to which she responded very well. Although viral infections have been related to Lemierre's syndrome, influenza virus rarely implicated. Lemierre's syndrome should be included in the differential diagnoses of rare complications of influenza virus infection.

摘要

我们报告了一名24岁既往健康的女性,在感染甲型流感病毒后患上了勒米尔综合征。在通过快速抗原检测诊断出甲型流感并用奥司他韦治疗一周后,她出现了多个肺空洞病变以及左侧颈内静脉血栓形成。血培养结果显示坏死梭杆菌生长。我们给予了氨苄西林-舒巴坦和普通肝素治疗,她对此反应良好。虽然病毒感染与勒米尔综合征有关,但流感病毒很少被牵连。在流感病毒感染罕见并发症的鉴别诊断中应考虑勒米尔综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79e2/7060288/ec309733051d/JGF2-21-18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79e2/7060288/ec309733051d/JGF2-21-18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79e2/7060288/ec309733051d/JGF2-21-18-g001.jpg

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本文引用的文献

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Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease.流感与细菌重叠感染:阐明疾病的免疫机制
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Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome.人类感染坏死梭杆菌(坏死杆菌病),重点关注勒米尔综合征。
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Lemierre's Syndrome.勒米尔综合征
Curr Infect Dis Rep. 2000 Apr;2(2):168-173. doi: 10.1007/s11908-000-0030-z.
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Postanginal sepsis following infectious mononucleosis.传染性单核细胞增多症后的咽峡炎败血症
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